Advanced search
Combine gene, variant, phenotype, region and year filters
Every result shows the extracted entities next to the sentences that support them; rows for the searched entities come first.
Transparent by designEvery result links extracted entities to its source sentence and publication identifier.
Knowledge-base search
About your search
ABCG2 and HIV infection are reported together in 2 articles.
Gene
ABCG2
- HGNC
- HGNC:74
21articles
21mentions
2variants with confirmed gene link
Most co-reported phenotypes (articles)
breast cancer 5HIV infection 2congenital myopathy 2dyslipidemia 2rheumatoid arthritis 2colorectal cancer 1ovarian cancer 1prostate cancer 1
Reported variants (articles · ClinVar status)
Phenotype
HIV infection
146articles
146mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
2 records shown · first 60ABCG2 polymorphisms and susceptibility to ARV-associated hepatotoxicity.
PMID 38451012 | PMCID PMC10955225 | DOI 10.1002/mgg3.2362 · Molecular genetics & genomic medicine · 2024 · 4 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | ABCG2 | “ABCG2 polymorphisms and susceptibility to ARV-associated hepatotoxicity.” | 0.98 | hgnc_dict_v1 |
| phenotype | HIV infection | “Moreover, when comparing HIV patients with hepatotoxicity to healthy controls, the haplotype GA had an association with an elevated risk for the development of hepatotoxicity (p = 0.041, OR = 1.73, 95% CI: 1.02-2.93).” | 0.93 | phenotype_alias_lexicon_v2 |
| variant | rs2231137 | “METHODS: To investigate this, we examined ABCG2 34G/A (rs2231137) and 421C/A (rs2231142) genetic variations in 149 HIV-infected patients (116 without hepatotoxicity, 33 with ARV-induced hepatotoxicity) and 151 healthy controls through the PCR-restriction fragment length polymorphism (PCR-RFLP) technique.” | 0.90 | hgvs_regex_v1 |
| variant | rs2231142 | “METHODS: To investigate this, we examined ABCG2 34G/A (rs2231137) and 421C/A (rs2231142) genetic variations in 149 HIV-infected patients (116 without hepatotoxicity, 33 with ARV-induced hepatotoxicity) and 151 healthy controls through the PCR-restriction fragment length polymorphism (PCR-RFLP) technique.” | 0.90 | hgvs_regex_v1 |
Role of HIV and Antiretroviral Therapy on the Expression of Placental Transporters in Women with HIV.
PMID 33099683 | DOI 10.1208/s12248-020-00516-2 · The AAPS journal · 2020 · 6 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | ABCG2 | “Several ABC (ABCG2, ABCC1,2,4) and SLC (SLC21A9, SLC22A1,3,11) transporters were significantly downregulated in placentas isolated from HIV(+) women as compared with HIV(-) controls (p < 0.05-0.001), while ABCB1 and SLC21A12 were significantly upregulated (p < 0.001).” | 0.98 | hgnc_dict_v1 |
| phenotype | HIV infection | “Role of HIV and Antiretroviral Therapy on the Expression of Placental Transporters in Women with HIV.” | 0.93 | phenotype_alias_lexicon_v2 |
| gene | ABCC1 | “Several ABC (ABCG2, ABCC1,2,4) and SLC (SLC21A9, SLC22A1,3,11) transporters were significantly downregulated in placentas isolated from HIV(+) women as compared with HIV(-) controls (p < 0.05-0.001), while ABCB1 and SLC21A12 were significantly upregulated (p < 0.001).” | 0.98 | hgnc_dict_v1 |
| gene | SLC22A1 | “Several ABC (ABCG2, ABCC1,2,4) and SLC (SLC21A9, SLC22A1,3,11) transporters were significantly downregulated in placentas isolated from HIV(+) women as compared with HIV(-) controls (p < 0.05-0.001), while ABCB1 and SLC21A12 were significantly upregulated (p < 0.001).” | 0.98 | hgnc_dict_v1 |