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ACE and pre-eclampsia are reported together in 3 articles.
Gene
ACE
- HGNC
- HGNC:2707
63articles
63mentions
2variants with confirmed gene link
Most co-reported phenotypes (articles)
diabetes mellitus 13COVID-19 8hypertension 7coronary artery disease 6obesity 5renal failure 4pre-eclampsia 3congenital heart disease 2
Reported variants (articles · ClinVar status)
Phenotype
Pre-eclampsia
84articles
84mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
3 records shown · first 60Association of ACE*(Insertion/Deletion) Variant with the Elevated Risk of Preeclampsia Among Gestational Women.
PMID 38219243 | DOI 10.1007/s10528-023-10620-5 · Biochemical genetics · 2024 · 2 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | ACE | “Association of ACE*(Insertion/Deletion) Variant with the Elevated Risk of Preeclampsia Among Gestational Women.” | 0.98 | hgnc_dict_v1 |
| phenotype | pre-eclampsia | “Association of ACE*(Insertion/Deletion) Variant with the Elevated Risk of Preeclampsia Among Gestational Women.” | 0.93 | phenotype_alias_lexicon_v2 |
Assessment of insertion/deletion polymorphism of ACE gene as a genetic risk marker for preeclampsia in pregnant women.
PMID 32400729 | DOI 10.5455/JPMA.11322 · JPMA. The Journal of the Pakistan Medical Association · 2020 · 3 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | ACE | “Assessment of insertion/deletion polymorphism of ACE gene as a genetic risk marker for preeclampsia in pregnant women.” | 0.98 | hgnc_dict_v1 |
| phenotype | pre-eclampsia | “Assessment of insertion/deletion polymorphism of ACE gene as a genetic risk marker for preeclampsia in pregnant women.” | 0.93 | phenotype_alias_lexicon_v2 |
| population | Saudi Arabia, Jeddah | “METHODS: The case-control study was conducted from January 2016 to December 2017 at King Abdulaziz University Hospital and Maternity & Children Hospital, Jeddah, Saudi Arabia, and comprised pregnant women withpreeclampsia as cases and normal pregnant women as controls.” | 0.95 | saudi_context_rules_v1 |
Role of ACE I/D polymorphism in pathological assessment of preeclampsia in Pakistan.
PMID 31173490 | PMCID PMC6625086 | DOI 10.1002/mgg3.799 · Molecular genetics & genomic medicine · 2019 · 2 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | ACE | “Role of ACE I/D polymorphism in pathological assessment of preeclampsia in Pakistan.” | 0.98 | hgnc_dict_v1 |
| phenotype | pre-eclampsia | “Role of ACE I/D polymorphism in pathological assessment of preeclampsia in Pakistan.” | 0.93 | phenotype_alias_lexicon_v2 |