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ACE2 and hepatitis C are reported together in 1 article.
Gene
ACE2
- HGNC
- HGNC:13557
115articles
115mentions
10variants with confirmed gene link (top 10)
Most co-reported phenotypes (articles)
COVID-19 81SARS 30hypertension 8MERS 6diabetes mellitus 6obesity 6coronary artery disease 3lung cancer 2
Reported variants (articles · ClinVar status)
Phenotype
Hepatitis C
421articles
421mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Linking COVID-19 and Parkinson's disease: Targeting the role of Vitamin-D.
PMID 34715496 | PMCID PMC8524705 | DOI 10.1016/j.bbrc.2021.10.042 · Biochemical and biophysical research communications · 2021 · 4 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | ACE2 | “SARS-CoV-2 invades cells via the ACE2 receptor, which is widely expressed in the central nervous system, where the virus may precipitate or accelerate dementia.” | 0.98 | hgnc_dict_v1 |
| phenotype | hepatitis C | “Coxsackievirus, dengue virus Epstein-Barr virus, hepatitis C virus, Japanese encephalitis, Western equine encephalomyelitis virus, West Nile virus, and human immunodeficiency virus have all been linked to the development of transient or permanent parkinsonism, owing to the induction of neuroinflammation/hypoxic brain injury with structural/functional damage within the basal ganglia.” | 0.98 | phenotype_alias_lexicon_v2 |
| phenotype | COVID-19 | “Linking COVID-19 and Parkinson's disease: Targeting the role of Vitamin-D.” | 0.98 | phenotype_alias_lexicon_v2 |
| phenotype | Parkinson disease | “Linking COVID-19 and Parkinson's disease: Targeting the role of Vitamin-D.” | 0.93 | phenotype_alias_lexicon_v2 |