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AKT1 and asthma are reported together in 2 articles.
Gene
AKT1
- HGNC
- HGNC:391
63articles
63mentions
0variants with confirmed gene link
Most co-reported phenotypes (articles)
Phenotype
Asthma
285articles
285mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
2 records shown · first 60Network Pharmacology and Molecular Docking Reveal Anti-Asthmatic Potential of Zephyranthes rosea Lindl. in an Ovalbumin-Induced Asthma Model.
PMID 39598467 | PMCID PMC11597469 | DOI 10.3390/ph17111558 · Pharmaceuticals (Basel, Switzerland) · 2024 · 2 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | AKT1 | “In silico analysis, particularly of the binding affinities of Z. rosea bulb phytoconstituents for IL6, AKT1, and Src, supported in vivo results.” | 0.98 | hgnc_dict_v1 |
| phenotype | asthma | “Network Pharmacology and Molecular Docking Reveal Anti-Asthmatic Potential of Zephyranthes rosea Lindl. in an Ovalbumin-Induced Asthma Model.” | 0.98 | phenotype_alias_lexicon_v2 |
Molecular mechanism of Ferula asafoetida for the treatment of asthma: Network pharmacology and molecular docking approach.
PMID 36568408 | PMCID PMC9772567 | DOI 10.1016/j.sjbs.2022.103527 · Saudi journal of biological sciences · 2023 · 4 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | AKT1 | “In present work, we explored a compound-target-pathway network and discovered that assafoetidin, cynaroside, farnesiferol-B, farnesiferol-C, galbanic-acid, and luteolin significantly influenced the development of asthma by targeting MAPK3, AKT1 and TNF genes.” | 0.98 | hgnc_dict_v1 |
| phenotype | asthma | “Molecular mechanism of Ferula asafoetida for the treatment of asthma: Network pharmacology and molecular docking approach.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | MAPK3 | “In present work, we explored a compound-target-pathway network and discovered that assafoetidin, cynaroside, farnesiferol-B, farnesiferol-C, galbanic-acid, and luteolin significantly influenced the development of asthma by targeting MAPK3, AKT1 and TNF genes.” | 0.98 | hgnc_dict_v1 |
| gene | TNF | “In present work, we explored a compound-target-pathway network and discovered that assafoetidin, cynaroside, farnesiferol-B, farnesiferol-C, galbanic-acid, and luteolin significantly influenced the development of asthma by targeting MAPK3, AKT1 and TNF genes.” | 0.98 | hgnc_dict_v1 |