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ALK and thyroid cancer are reported together in 1 article.
Gene
ALK
- HGNC
- HGNC:427
31articles
31mentions
1variants with confirmed gene link
Most co-reported phenotypes (articles)
Reported variants (articles · ClinVar status)
Phenotype
Thyroid cancer
216articles
216mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Analysis of ALK, IDH1, IDH2 and MMP8 somatic mutations in differentiated thyroid cancers.
PMID 34462665 | PMCID PMC8375036 | DOI 10.3892/mco.2021.2373 · Molecular and clinical oncology · 2021 · 9 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | ALK | “Analysis of ALK, IDH1, IDH2 and MMP8 somatic mutations in differentiated thyroid cancers.” | 0.98 | hgnc_dict_v1 |
| phenotype | thyroid cancer | “Conversely, analyses of 117 aggressive thyroid cancers [84, poorly differentiated thyroid cancer (PDTC); 33, anaplastic thyroid cancer (ATC)] from the Memorial Sloan Kettering Cancer Center cohort revealed ALK mutations in 3% of ATCs and fusions in 3.6% of PDTCs.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | IDH1 | “Analysis of ALK, IDH1, IDH2 and MMP8 somatic mutations in differentiated thyroid cancers.” | 0.98 | hgnc_dict_v1 |
| gene | IDH2 | “Analysis of ALK, IDH1, IDH2 and MMP8 somatic mutations in differentiated thyroid cancers.” | 0.98 | hgnc_dict_v1 |