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APLP1 and metabolic syndrome are reported together in 1 article.
Gene
APLP1
- HGNC
- HGNC:597
1articles
1mentions
0variants with confirmed gene link
Most co-reported phenotypes (articles)
Phenotype
Metabolic syndrome
141articles
141mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Strain-based and sex-biased differences in adrenal and pancreatic gene expression between KK/HlJ and C57BL/6 J mice.
PMID 33711921 | PMCID PMC7953684 | DOI 10.1186/s12864-021-07495-4 · BMC genomics · 2021 · 9 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | APLP1 | “We established a network of functionally related DEGs commonly upregulated in both endocrine tissues of KK/HlJ mice which included the genes coding for endocrine secretory vesicle biogenesis and regulation: PCSK2, PCSK1N, SCG5, PTPRN, CHGB and APLP1.” | 0.98 | hgnc_dict_v1 |
| phenotype | metabolic syndrome | “The KK mouse strain has been used to study aspects of the metabolic syndrome and prediabetes.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | PCSK2 | “We established a network of functionally related DEGs commonly upregulated in both endocrine tissues of KK/HlJ mice which included the genes coding for endocrine secretory vesicle biogenesis and regulation: PCSK2, PCSK1N, SCG5, PTPRN, CHGB and APLP1.” | 0.98 | hgnc_dict_v1 |
| gene | PCSK1N | “We established a network of functionally related DEGs commonly upregulated in both endocrine tissues of KK/HlJ mice which included the genes coding for endocrine secretory vesicle biogenesis and regulation: PCSK2, PCSK1N, SCG5, PTPRN, CHGB and APLP1.” | 0.98 | hgnc_dict_v1 |