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BRCA1 and hepatocellular carcinoma are reported together in 1 article.
Gene
BRCA1
- HGNC
- HGNC:1100
132articles
132mentions
5variants with confirmed gene link
Most co-reported phenotypes (articles)
breast cancer 92ovarian cancer 26prostate cancer 9colorectal cancer 5diabetes mellitus 3gastric cancer 3leukemia 3lung cancer 3
Reported variants (articles · ClinVar status)
Phenotype
Hepatocellular carcinoma
417articles
417mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Anthocyanins: From Natural Colorants to Potent Anticancer Agents.
PMID 40321606 | PMCID PMC12048707 | DOI 10.1002/fsn3.70232 · Food science & nutrition · 2025 · 6 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | BRCA1 | “Moreover, anthocyanins downregulate oncogenes (Bcl-2, MYC, and HER2) and improve the activity of tumor suppressor genes (TP53, BRCA1, and RB1).” | 0.98 | hgnc_dict_v1 |
| phenotype | hepatocellular carcinoma | “Anthocyanins, particularly cyanidin-3-O-glucoside, suppress inflammation and production of pro-inflammatory cytokines (COX-2, TNF-α, and IL-6) in colorectal cancer and hepatocellular carcinoma.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | MYC | “Moreover, anthocyanins downregulate oncogenes (Bcl-2, MYC, and HER2) and improve the activity of tumor suppressor genes (TP53, BRCA1, and RB1).” | 0.98 | hgnc_dict_v1 |
| gene | TP53 | “Moreover, anthocyanins downregulate oncogenes (Bcl-2, MYC, and HER2) and improve the activity of tumor suppressor genes (TP53, BRCA1, and RB1).” | 0.98 | hgnc_dict_v1 |