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BRCA2 and gastric cancer are reported together in 3 articles.
Gene
BRCA2
- HGNC
- HGNC:1101
95articles
95mentions
6variants with confirmed gene link
Most co-reported phenotypes (articles)
breast cancer 57ovarian cancer 18prostate cancer 10colorectal cancer 6thyroid cancer 4gastric cancer 3leukemia 3diabetes mellitus 1
Reported variants (articles · ClinVar status)
Phenotype
Gastric cancer
106articles
106mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
3 records shown · first 60STK11 and DNA Repair Gene Mutations Define Hereditary Subset of Middle Eastern Papillary Thyroid Cancer.
PMID 41898519 | PMCID PMC13026885 | DOI 10.3390/ijms27062656 · International journal of molecular sciences · 2026 · 16 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | BRCA2 | “Eleven patients (4.5%) harbored germline PVs/LPVs in cancer susceptibility genes including STK11, TP53, BRCA1, BRCA2, FANCA, SLX4, RAD50, MSH6, POLD1 and NF1.” | 0.98 | hgnc_dict_v1 |
| phenotype | gastric cancer | “A TP53 hotspot mutation (p.R175H) was identified in a patient with a personal history of gastric cancer, a malignancy associated with Li-Fraumeni syndrome.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | STK11 | “STK11 and DNA Repair Gene Mutations Define Hereditary Subset of Middle Eastern Papillary Thyroid Cancer.” | 0.98 | hgnc_dict_v1 |
| gene | TP53 | “Eleven patients (4.5%) harbored germline PVs/LPVs in cancer susceptibility genes including STK11, TP53, BRCA1, BRCA2, FANCA, SLX4, RAD50, MSH6, POLD1 and NF1.” | 0.98 | hgnc_dict_v1 |
Exploration of BRCA1 and BRCA2 mutations in gastric cancer patients through next generation sequencing: implications for diagnosis and therapy.
PMID 39544817 | PMCID PMC11558441 | DOI 10.62347/KJYY7691 · American journal of translational research · 2024 · 5 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | BRCA2 | “Exploration of BRCA1 and BRCA2 mutations in gastric cancer patients through next generation sequencing: implications for diagnosis and therapy.” | 0.98 | hgnc_dict_v1 |
| phenotype | gastric cancer | “Exploration of BRCA1 and BRCA2 mutations in gastric cancer patients through next generation sequencing: implications for diagnosis and therapy.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | BRCA1 | “Exploration of BRCA1 and BRCA2 mutations in gastric cancer patients through next generation sequencing: implications for diagnosis and therapy.” | 0.98 | hgnc_dict_v1 |
| phenotype | breast cancer | “METHODOLOGY: In this study, we investigated the role of Breast Cancer gene 1 (BRCA1) and Breast Cancer gene 2 (BRCA2) mutations in Pakistani GC patients and their functional implications using Next-Generation Sequencing (NGS).” | 0.98 | phenotype_alias_lexicon_v2 |
Detection of genomic variants in BRCA1 and BRCA2 across gastric cancer patients using next generation sequencing.
PMID 39822496 | PMCID PMC11733335 | DOI 10.62347/MRIE2131 · American journal of translational research · 2024 · 3 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | BRCA2 | “Detection of genomic variants in BRCA1 and BRCA2 across gastric cancer patients using next generation sequencing.” | 0.98 | hgnc_dict_v1 |
| phenotype | gastric cancer | “Detection of genomic variants in BRCA1 and BRCA2 across gastric cancer patients using next generation sequencing.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | BRCA1 | “Detection of genomic variants in BRCA1 and BRCA2 across gastric cancer patients using next generation sequencing.” | 0.98 | hgnc_dict_v1 |