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C5 and MERS are reported together in 1 article.
Gene
C5
- HGNC
- HGNC:1331
9articles
9mentions
4variants with confirmed gene link
Most co-reported phenotypes (articles)
Reported variants (articles · ClinVar status)
Phenotype
MERS
230articles
230mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Epidemiology and evolution of Middle East respiratory syndrome coronavirus, 2012-2020.
PMID 33964965 | PMCID PMC8105704 | DOI 10.1186/s40249-021-00853-0 · Infectious diseases of poverty · 2021 · 3 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | C5 | “The most recent sub-clade C5.1 (since 2013) was associated with non-synonymous mutations and a higher mortality rate.” | 0.98 | hgnc_dict_v1 |
| phenotype | MERS | “Epidemiology and evolution of Middle East respiratory syndrome coronavirus, 2012-2020.” | 0.93 | phenotype_alias_lexicon_v2 |
| population | Saudi Arabia, Riyadh | “RESULTS: A total of 2562 confirmed MERS cases with 150 case clusters were reported with a case fatality rate of 32.7% (95% CI: 30.9‒34.6%). Saudi Arabia accounted for 83.6% of the cases. Diffusion of the disease was fastest from its origin in Saudi Arabia to the east, and was primarily driven by the transportation network. Phylogeographic analyses pointed to Riyadh of Saudi Arabia and Abu Dhabi of the United Arab Emirates as the hubs for both local and international spread of MERS-CoV.” | 0.95 | saudi_context_rules_v1 |