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CA2 and thyroid cancer are reported together in 1 article.
Gene
CA2
- HGNC
- HGNC:1373
6articles
6mentions
0variants with confirmed gene link
Most co-reported phenotypes (articles)
Phenotype
Thyroid cancer
216articles
216mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Meta-analysis of whole-genome gene expression datasets assessing the effects of IDH1 and IDH2 mutations in isogenic disease models.
PMID 34997121 | PMCID PMC8741954 | DOI 10.1038/s41598-021-04214-7 · Scientific reports · 2022 · 10 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | CA2 | “Carbonic anhydrase 2 (CA2) and prolyl 3-hydroxylase 2 (P3H2) were upregulated in three datasets, and SOX2 overlapping transcript (SOX2-OT) was downregulated in three datasets.” | 0.98 | hgnc_dict_v1 |
| phenotype | thyroid cancer | “Mutations in isocitrate dehydrogenase 1 (IDH1) and IDH2 are oncogenic drivers to a variable extent in several tumors, including gliomas, acute myeloid leukemia (AML), cholangiocarcinoma, melanoma, and thyroid carcinoma.” | 0.93 | phenotype_alias_lexicon_v2 |
| gene | IDH1 | “Meta-analysis of whole-genome gene expression datasets assessing the effects of IDH1 and IDH2 mutations in isogenic disease models.” | 0.98 | hgnc_dict_v1 |
| gene | IDH2 | “Meta-analysis of whole-genome gene expression datasets assessing the effects of IDH1 and IDH2 mutations in isogenic disease models.” | 0.98 | hgnc_dict_v1 |