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CCL2 and COVID-19 are reported together in 2 articles.
Gene
CCL2
- HGNC
- HGNC:10618
35articles
35mentions
2variants with confirmed gene link
Most co-reported phenotypes (articles)
diabetes mellitus 4lung cancer 3COVID-19 2metabolic syndrome 2MERS 1amyotrophic lateral sclerosis 1hepatitis C 1obesity 1
Reported variants (articles · ClinVar status)
Phenotype
COVID-19
1,317articles
1,317mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
2 records shown · first 60Profile of Circulatory Cytokines and Chemokines in Human Coronaviruses: A Systematic Review and Meta-Analysis.
PMID 34046036 | PMCID PMC8147689 | DOI 10.3389/fimmu.2021.666223 · Frontiers in immunology · 2021 · 4 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | CCL2 | “Increased circulating levels of CXCL10/IP10 and CCL2/MCP-1 might also be related to the severity of MERS.” | 0.98 | hgnc_dict_v1 |
| phenotype | COVID-19 | “BACKGROUND: SARS, MERS, and COVID-19 share similar characteristics.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | CXCL10 | “Increased circulating levels of CXCL10/IP10 and CCL2/MCP-1 might also be related to the severity of MERS.” | 0.98 | hgnc_dict_v1 |
| phenotype | MERS | “BACKGROUND: SARS, MERS, and COVID-19 share similar characteristics.” | 0.98 | phenotype_alias_lexicon_v2 |
The Rise of SARS-CoV-2 Variants and the Role of Convalescent Plasma Therapy for Management of Infections.
PMID 34440478 | PMCID PMC8399171 | DOI 10.3390/life11080734 · Life (Basel, Switzerland) · 2021 · 2 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | CCL2 | “Convalescent plasma is rich with cytokines (IL-1β, IL-2, IL-6, IL-17, and IL-8), CCL2, and TNFα, neutralizing antibodies, and clotting factors essential for the management of SARS-CoV-2 infection.” | 0.98 | hgnc_dict_v1 |
| phenotype | COVID-19 | “Novel therapies for the treatment of COVID-19 are continuing to emerge as the SARS-Cov-2 pandemic progresses.” | 0.98 | phenotype_alias_lexicon_v2 |