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Every result shows the extracted entities next to the sentences that support them; rows for the searched entities come first.
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CCL2 and amyotrophic lateral sclerosis are reported together in 1 article.
Gene
CCL2
- HGNC
- HGNC:10618
35articles
35mentions
2variants with confirmed gene link
Most co-reported phenotypes (articles)
diabetes mellitus 4lung cancer 3COVID-19 2metabolic syndrome 2MERS 1amyotrophic lateral sclerosis 1hepatitis C 1obesity 1
Reported variants (articles · ClinVar status)
Phenotype
Amyotrophic lateral sclerosis
105articles
105mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60The CCL2-CCR2 axis drives neuromuscular denervation in amyotrophic lateral sclerosis.
PMID 40750607 | PMCID PMC12316999 | DOI 10.1038/s41467-025-62351-3 · Nature communications · 2025 · 2 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | CCL2 | “CCL2+ cells were enriched around NMJs in hTDP-43 mice, and in ALS patient skeletal muscle.” | 0.98 | hgnc_dict_v1 |
| phenotype | amyotrophic lateral sclerosis | “The CCL2-CCR2 axis drives neuromuscular denervation in amyotrophic lateral sclerosis.” | 0.98 | phenotype_alias_lexicon_v2 |