Advanced search
Combine gene, variant, phenotype, region and year filters
Every result shows the extracted entities next to the sentences that support them; rows for the searched entities come first.
Transparent by designEvery result links extracted entities to its source sentence and publication identifier.
Knowledge-base search
About your search
CD14 and multiple sclerosis are reported together in 2 articles.
Gene
CD14
- HGNC
- HGNC:1628
51articles
51mentions
1variants with confirmed gene link
Most co-reported phenotypes (articles)
autism spectrum disorder 5leukemia 4neurodevelopmental disorder 4asthma 3obesity 3diabetes mellitus 2multiple sclerosis 2tuberculosis 2
Reported variants (articles · ClinVar status)
Phenotype
Multiple sclerosis
236articles
236mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
2 records shown · first 60Deep characterization of paired chromatin and transcriptomes in four immune cell types from multiple sclerosis patients.
PMID 34676774 | DOI 10.2217/epi-2021-0205 · Epigenomics · 2021 · 5 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | CD14 | “Material & methods: We generated paired assay for transposase-accessible chromatin sequencing and RNA-sequencing profiles from sorted blood immune CD4+ and CD8+ T cells, CD14+ monocytes and CD19+ B cells from healthy controls (HCs) and MS patients.” | 0.98 | hgnc_dict_v1 |
| phenotype | multiple sclerosis | “Deep characterization of paired chromatin and transcriptomes in four immune cell types from multiple sclerosis patients.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | CD4 | “Material & methods: We generated paired assay for transposase-accessible chromatin sequencing and RNA-sequencing profiles from sorted blood immune CD4+ and CD8+ T cells, CD14+ monocytes and CD19+ B cells from healthy controls (HCs) and MS patients.” | 0.98 | hgnc_dict_v1 |
| gene | CD19 | “Material & methods: We generated paired assay for transposase-accessible chromatin sequencing and RNA-sequencing profiles from sorted blood immune CD4+ and CD8+ T cells, CD14+ monocytes and CD19+ B cells from healthy controls (HCs) and MS patients.” | 0.98 | hgnc_dict_v1 |
Combining evidence from four immune cell types identifies DNA methylation patterns that implicate functionally distinct pathways during Multiple Sclerosis progression.
PMID 31053557 | PMCID PMC6558224 | DOI 10.1016/j.ebiom.2019.04.042 · EBioMedicine · 2019 · 3 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | CD14 | “METHODS: We measured DNA methylation in CD4+ T cells (n = 31), CD8+ T cells (n = 28), CD14+ monocytes (n = 35) and CD19+ B cells (n = 27) from relapsing-remitting (RRMS), secondary progressive (SPMS) patients and healthy controls (HC) using Infinium HumanMethylation450 arrays.” | 0.98 | hgnc_dict_v1 |
| phenotype | multiple sclerosis | “Combining evidence from four immune cell types identifies DNA methylation patterns that implicate functionally distinct pathways during Multiple Sclerosis progression.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | CD19 | “METHODS: We measured DNA methylation in CD4+ T cells (n = 31), CD8+ T cells (n = 28), CD14+ monocytes (n = 35) and CD19+ B cells (n = 27) from relapsing-remitting (RRMS), secondary progressive (SPMS) patients and healthy controls (HC) using Infinium HumanMethylation450 arrays.” | 0.98 | hgnc_dict_v1 |