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CD38 and diabetes mellitus are reported together in 2 articles.
Gene
CD38
- HGNC
- HGNC:1667
22articles
22mentions
0variants with confirmed gene link
Most co-reported phenotypes (articles)
Phenotype
Diabetes mellitus
2,156articles
2,156mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
2 records shown · first 60Dysregulation of Niacin-Derived NAD+ Salvage Pathway Markers (CD38, NAMPT, SIRT1) Across Albuminuria Stages in Type 2 Diabetes.
PMID 41470091 | PMCID PMC12735112 | DOI 10.3390/medicina61122089 · Medicina (Kaunas, Lithuania) · 2025 · 5 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | CD38 | “Dysregulation of Niacin-Derived NAD+ Salvage Pathway Markers (CD38, NAMPT, SIRT1) Across Albuminuria Stages in Type 2 Diabetes.” | 0.98 | hgnc_dict_v1 |
| phenotype | diabetes mellitus | “Dysregulation of Niacin-Derived NAD+ Salvage Pathway Markers (CD38, NAMPT, SIRT1) Across Albuminuria Stages in Type 2 Diabetes.” | 0.93 | phenotype_alias_lexicon_v2 |
| gene | NAMPT | “Dysregulation of Niacin-Derived NAD+ Salvage Pathway Markers (CD38, NAMPT, SIRT1) Across Albuminuria Stages in Type 2 Diabetes.” | 0.98 | hgnc_dict_v1 |
| gene | SIRT1 | “Dysregulation of Niacin-Derived NAD+ Salvage Pathway Markers (CD38, NAMPT, SIRT1) Across Albuminuria Stages in Type 2 Diabetes.” | 0.98 | hgnc_dict_v1 |
Angiotensin II modulates THP-1-like macrophage phenotype and inflammatory signatures via angiotensin II type 1 receptor.
PMID 37692050 | PMCID PMC10485254 | DOI 10.3389/fcvm.2023.1129704 · Frontiers in cardiovascular medicine · 2023 · 5 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | CD38 | “Yet, Ang II increased the expression of proinflammatory markers (HLA-DR, TNF-α, CD64, CD11c, and CD38) and decreased CD206 (mannose receptor), an M2 marker.” | 0.98 | hgnc_dict_v1 |
| phenotype | diabetes mellitus | “Recently, long-term metabolomics studies have linked high levels of angiotensin plasma to inflammatory conditions such as coronary heart disease, obesity, and type 2 diabetes.” | 0.93 | phenotype_alias_lexicon_v2 |
| gene | CD44 | “Ang II stimulated the expression of markers involved in monocyte/macrophage cell differentiation (e.g., CD116), as well as adhesion, cell-cell interaction, chemotaxis, and phagocytosis (CD15, CD44, CD33, and CD49F).” | 0.98 | hgnc_dict_v1 |
| gene | CD33 | “Ang II stimulated the expression of markers involved in monocyte/macrophage cell differentiation (e.g., CD116), as well as adhesion, cell-cell interaction, chemotaxis, and phagocytosis (CD15, CD44, CD33, and CD49F).” | 0.98 | hgnc_dict_v1 |