Advanced search
Combine gene, variant, phenotype, region and year filters
Every result shows the extracted entities next to the sentences that support them; rows for the searched entities come first.
Transparent by designEvery result links extracted entities to its source sentence and publication identifier.
Knowledge-base search
About your search
CD40 and hepatitis B are reported together in 1 article.
Gene
CD40
- HGNC
- HGNC:11919
24articles
24mentions
2variants with confirmed gene link
Most co-reported phenotypes (articles)
autism spectrum disorder 4neurodevelopmental disorder 3rheumatoid arthritis 3leukemia 2pre-eclampsia 2recurrent pregnancy loss 2Down syndrome 1Klinefelter syndrome 1
Reported variants (articles · ClinVar status)
Phenotype
Hepatitis B
255articles
255mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Host genetic factors in predicting response status in chronic hepatitis B patients discontinuing nucleos(t)ide analogs.
PMID 29451182 | PMCID PMC5848322 | DOI 10.4103/sjg.SJG_228_17 · Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2018 · 4 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | CD40 | “RESULTS: Seventy-six CHB patients were enrolled in our study, of which 61 patients were HBeAg-positive and 15 patients were HBeAg-negative. rs1883832 in the Kozak sequence of CD40 displayed an AUROC of 0.778 in predicting response status in CHB patients with HBeAg seroconversion and a genotype of CT was associated with sustained response in this subpopulation.” | 0.98 | hgnc_dict_v1 |
| phenotype | hepatitis B | “Host genetic factors in predicting response status in chronic hepatitis B patients discontinuing nucleos(t)ide analogs.” | 0.98 | phenotype_alias_lexicon_v2 |
| variant | rs1883832 | “RESULTS: Seventy-six CHB patients were enrolled in our study, of which 61 patients were HBeAg-positive and 15 patients were HBeAg-negative. rs1883832 in the Kozak sequence of CD40 displayed an AUROC of 0.778 in predicting response status in CHB patients with HBeAg seroconversion and a genotype of CT was associated with sustained response in this subpopulation.” | 0.90 | hgvs_regex_v1 |
| variant | rs9277535 | “For HBeAg-negative CHB patients, rs9277535 at HLA-DP presents a Spearman correlation coefficient of 0.582 (P = 0.023) with virological relapse after discontinuation of NAs.” | 0.90 | hgvs_regex_v1 |