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CDC42 and breast cancer are reported together in 2 articles.
Gene
CDC42
- HGNC
- HGNC:1736
11articles
11mentions
0variants with confirmed gene link
Most co-reported phenotypes (articles)
Phenotype
Breast cancer
1,211articles
1,211mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
2 records shown · first 60Subtype-Specific m6A circRNA Methylation Patterns Identify Epigenetic Biomarker Candidates of Potential Diagnostic and Prognostic Significance in Breast Cancer.
PMID 41516402 | PMCID PMC12786885 | DOI 10.3390/ijms27010529 · International journal of molecular sciences · 2026 · 6 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | CDC42 | “Distinct m6A circRNA methylation signatures were identified across breast cancer subtypes, with TNBC showing enrichment in pathways related to Wnt/β-catenin, CDC42 GTPase signaling, and cytoskeletal remodeling.” | 0.98 | hgnc_dict_v1 |
| phenotype | breast cancer | “Subtype-Specific m6A circRNA Methylation Patterns Identify Epigenetic Biomarker Candidates of Potential Diagnostic and Prognostic Significance in Breast Cancer.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | ZBTB16 | “Several circRNAs, including those derived from ZBTB16, DOCK1, METTL8, and VAV3, exhibited significant hypermethylation and high diagnostic accuracy (AUC > 0.80).” | 0.98 | hgnc_dict_v1 |
| gene | DOCK1 | “Several circRNAs, including those derived from ZBTB16, DOCK1, METTL8, and VAV3, exhibited significant hypermethylation and high diagnostic accuracy (AUC > 0.80).” | 0.98 | hgnc_dict_v1 |
Elevated MMP9 expression in breast cancer is a predictor of shorter patient survival.
PMID 32445177 | PMCID PMC7297818 | DOI 10.1007/s10549-020-05670-x · Breast cancer research and treatment · 2020 · 5 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | CDC42 | “Elevated MMP9 protein expression correlated significantly with cytokeratin 17 (Ck17), Epidermal Growth Factor Receptor (EGFR), proliferation (Ki67) biomarkers, cell surface adhesion receptor (CD44) and cell division control protein 42 (CDC42).” | 0.98 | hgnc_dict_v1 |
| phenotype | breast cancer | “Elevated MMP9 expression in breast cancer is a predictor of shorter patient survival.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | MMP9 | “Elevated MMP9 expression in breast cancer is a predictor of shorter patient survival.” | 0.98 | hgnc_dict_v1 |
| gene | EGFR | “Elevated MMP9 protein expression correlated significantly with cytokeratin 17 (Ck17), Epidermal Growth Factor Receptor (EGFR), proliferation (Ki67) biomarkers, cell surface adhesion receptor (CD44) and cell division control protein 42 (CDC42).” | 0.98 | hgnc_dict_v1 |