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CDK6 and breast cancer are reported together in 2 articles.
Gene
CDK6
- HGNC
- HGNC:1777
5articles
5mentions
0variants with confirmed gene link
Most co-reported phenotypes (articles)
Phenotype
Breast cancer
1,211articles
1,211mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
2 records shown · first 60Neoadjuvant endocrine therapy with or without palbociclib in low-risk patients: a phase III randomized double-blind SAFIA trial.
PMID 36680581 | PMCID PMC9864499 | DOI 10.1007/s00432-023-04588-3 · Journal of cancer research and clinical oncology · 2023 · 3 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | CDK6 | “OBJECTIVE: Analyze the complete pathologic response (pCR) rate and overall response in a low-risk hormone-positive subset of patients receiving neoadjuvant hormone treatment (NAHT) with or without Palbociclib (a CDK4/CDK6 inhibitor) to boost NAHT effectiveness.” | 0.98 | hgnc_dict_v1 |
| phenotype | breast cancer | “BACKGROUND: The most prevalent subtype of breast cancer (BC) is luminal hormonal-positive breast cancer.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | CDK4 | “OBJECTIVE: Analyze the complete pathologic response (pCR) rate and overall response in a low-risk hormone-positive subset of patients receiving neoadjuvant hormone treatment (NAHT) with or without Palbociclib (a CDK4/CDK6 inhibitor) to boost NAHT effectiveness.” | 0.98 | hgnc_dict_v1 |
Gene expression profiling in women with breast cancer in a Saudi population.
PMID 18382789 · Saudi medical journal · 2008 · 5 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | CDK6 | “We also suggest 3 differentially-expressed genes IGHG3, CDK6, and RPS9 in tumors may have a novel role in breast cancer.” | 0.98 | hgnc_dict_v1 |
| phenotype | breast cancer | “Gene expression profiling in women with breast cancer in a Saudi population.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | IGHG3 | “We also suggest 3 differentially-expressed genes IGHG3, CDK6, and RPS9 in tumors may have a novel role in breast cancer.” | 0.98 | hgnc_dict_v1 |
| gene | RPS9 | “We also suggest 3 differentially-expressed genes IGHG3, CDK6, and RPS9 in tumors may have a novel role in breast cancer.” | 0.98 | hgnc_dict_v1 |