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Every result shows the extracted entities next to the sentences that support them; rows for the searched entities come first.
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CREB1 and diabetes mellitus are reported together in 1 article.
Gene
CREB1
- HGNC
- HGNC:2345
7articles
7mentions
0variants with confirmed gene link
Most co-reported phenotypes (articles)
Phenotype
Diabetes mellitus
2,156articles
2,156mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Biological impact of advanced glycation endproducts on estrogen receptor-positive MCF-7 breast cancer cells.
PMID 28712835 | DOI 10.1016/j.bbadis.2017.07.011 · Biochimica et biophysica acta. Molecular basis of disease · 2017 · 3 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | CREB1 | “A phospho-protein array analysis revealed that AGEs mainly induce the phosphorylation of extracellular-signal regulated kinase (ERK)1/2 and cAMP response element binding protein-1 (CREB1), both signaling molecules considered as key regulators of AGEs pro-tumorigenic effects.” | 0.98 | hgnc_dict_v1 |
| phenotype | diabetes mellitus | “Diabetes mellitus potentiates the risk of breast cancer.” | 0.98 | phenotype_alias_lexicon_v2 |
| phenotype | breast cancer | “Biological impact of advanced glycation endproducts on estrogen receptor-positive MCF-7 breast cancer cells.” | 0.98 | phenotype_alias_lexicon_v2 |