Advanced search
Combine gene, variant, phenotype, region and year filters
Every result shows the extracted entities next to the sentences that support them; rows for the searched entities come first.
Transparent by designEvery result links extracted entities to its source sentence and publication identifier.
Knowledge-base search
About your search
CRP and obesity are reported together in 3 articles.
Gene
CRP
- HGNC
- HGNC:2367
34articles
34mentions
0variants with confirmed gene link
Most co-reported phenotypes (articles)
Phenotype
Obesity
- HPO
- HP:0001513
856articles
856mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
3 records shown · first 60Genetic Variants of HNF4A, WFS1, DUSP9, FTO, and ZFAND6 Genes Are Associated with Prediabetes Susceptibility and Inflammatory Markers in the Saudi Arabian Population.
PMID 36980809 | PMCID PMC10048403 | DOI 10.3390/genes14030536 · Genes · 2023 · 14 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | CRP | “Additionally, C-reactive protein (CRP) levels in rs11634397 (AA) with a median of 5389.0 (2767.4-7412.8) were significantly higher than in the heterozygous GA genotype with a median of 1736.3 (1024.4-4452.0) (p < 0.01).” | 0.98 | hgnc_dict_v1 |
| phenotype | obesity | “In conclusion, only five of the 37 genetic variants previously linked to T2DM and obesity in the Saudi Arabian population [HNF4A-rs4812829, WFS1-rs1801214, DUSP9-rs5945326, ZFAND6-rs11634397, FTO-rs11642841] were associated with prediabetes susceptibility.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | HNF4A | “Genetic Variants of HNF4A, WFS1, DUSP9, FTO, and ZFAND6 Genes Are Associated with Prediabetes Susceptibility and Inflammatory Markers in the Saudi Arabian Population.” | 0.98 | hgnc_dict_v1 |
| gene | WFS1 | “Genetic Variants of HNF4A, WFS1, DUSP9, FTO, and ZFAND6 Genes Are Associated with Prediabetes Susceptibility and Inflammatory Markers in the Saudi Arabian Population.” | 0.98 | hgnc_dict_v1 |
Increased TNF α, IL-6 and ErbB2 mRNA expression in peripheral blood leukocytes from breast cancer patients.
PMID 24961464 | DOI 10.1007/s12032-014-0038-0 · Medical oncology (Northwood, London, England) · 2014 · 7 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | CRP | “Therefore, have investigated whether or not the expression levels, of selected genes [tumor necrosis factor-α (TNFα), interleukin 6 (IL-6), adiponectin, leptin, C-reactive protein (CRP), parathyroid hormone (PTH), tumor protein 53 (TP53) and erythroblastic leukemia viral oncogene 2 (ErbB2)] were altered in blood samples of lean, overweight/obese and breast cancer subjects.” | 0.98 | hgnc_dict_v1 |
| phenotype | obesity | “Obesity has been associated with increased incidence and mortality of breast cancer.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | TNF | “Increased TNF α, IL-6 and ErbB2 mRNA expression in peripheral blood leukocytes from breast cancer patients.” | 0.98 | hgnc_dict_v1 |
| gene | PTH | “Therefore, have investigated whether or not the expression levels, of selected genes [tumor necrosis factor-α (TNFα), interleukin 6 (IL-6), adiponectin, leptin, C-reactive protein (CRP), parathyroid hormone (PTH), tumor protein 53 (TP53) and erythroblastic leukemia viral oncogene 2 (ErbB2)] were altered in blood samples of lean, overweight/obese and breast cancer subjects.” | 0.98 | hgnc_dict_v1 |
Inflammatory markers and haptoglobin polymorphism in Saudi with non-insulin-dependent diabetes mellitus.
PMID 23283045 | PMCID PMC4776982 | DOI 10.5539/gjhs.v5n1p135 · Global journal of health science · 2012 · 4 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | CRP | “In addition to Hp; other possible genetic polymorphisms like CRP may have its effect on diabetes through different mechanisms.” | 0.98 | hgnc_dict_v1 |
| phenotype | obesity | “CONCLUSION: Inflammation may represent the link between type 2 diabetes and obesity.” | 0.98 | phenotype_alias_lexicon_v2 |
| phenotype | diabetes mellitus | “Inflammatory markers and haptoglobin polymorphism in Saudi with non-insulin-dependent diabetes mellitus.” | 0.98 | phenotype_alias_lexicon_v2 |
| population | Saudi Arabia | “Inflammatory markers and haptoglobin polymorphism in Saudi with non-insulin-dependent diabetes mellitus. We designed the present study to investigate the frequency distribution of Hp phenotypes among Saudi with non-insulin-dependent diabetes mellitus compared to healthy nondiabetic subjects. METHODS: In the present case-control study, we enrolled 60 type 2 diabetic patients as the study group and 60 healthy subjects as the control group. Hp 2-1 was the predominant phenotype among Saudi type 2 diabetics as well as healthy subjects.” | 0.95 | saudi_context_rules_v1 |