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CS and leukemia are reported together in 1 article.
Gene
CS
- HGNC
- HGNC:2422
20articles
20mentions
0variants with confirmed gene link
Most co-reported phenotypes (articles)
Phenotype
Leukemia
652articles
652mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Cigarette smoke modulates methylation levels of LEF1-AS1 and impedes its expression: An experimental study.
PMID 40321723 | PMCID PMC12046985 | DOI 10.18332/tid/203507 · Tobacco induced diseases · 2025 · 4 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | CS | “INTRODUCTION: Cigarette smoke (CS) contains carcinogenic substances and influences genetic regulation and epigenetic modifications, such as DNA methylation.” | 0.98 | hgnc_dict_v1 |
| phenotype | leukemia | “It plays a role in the development of various cancers, including colon, bladder, lung cancer, and leukemia.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | LEF1-AS1 | “Cigarette smoke modulates methylation levels of LEF1-AS1 and impedes its expression: An experimental study.” | 0.98 | hgnc_dict_v1 |
| phenotype | lung cancer | “It plays a role in the development of various cancers, including colon, bladder, lung cancer, and leukemia.” | 0.98 | phenotype_alias_lexicon_v2 |