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CTLA4 and lung cancer are reported together in 1 article.
Gene
CTLA4
- HGNC
- HGNC:2505
23articles
23mentions
8variants with confirmed gene link
Most co-reported phenotypes (articles)
breast cancer 4systemic lupus erythematosus 3atopic dermatitis 1hemophilia 1hepatitis C 1leukemia 1lung cancer 1
Reported variants (articles · ClinVar status)
Phenotype
Lung cancer
398articles
398mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Evaluation of PD-L1 Expression and Systemic Inflammatory Blood Cell Ratios as Prognosticators in Advanced Lung, Breast and Head and Neck Cancers.
PMID 42279401 | PMCID PMC13255956 | DOI 10.3390/cancers18111819 · Cancers · 2026 · 3 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | CTLA4 | “Bioinformatics analysis identified several PD-L1-interacting genes, including PD-1, CTLA4 and PTPN and demonstrated strong positive correlations between PD-L1 expression and the infiltration of CD8+ T cells, neutrophils and dendritic cells across the analysed malignancies.” | 0.98 | hgnc_dict_v1 |
| phenotype | lung cancer | “RESULTS: PD-L1 positivity (≥1%) was observed in 56.75% of lung cancer cases, 44% of breast cancer cases and 92.85% of head and neck cancer cases.” | 0.98 | phenotype_alias_lexicon_v2 |
| phenotype | breast cancer | “RESULTS: PD-L1 positivity (≥1%) was observed in 56.75% of lung cancer cases, 44% of breast cancer cases and 92.85% of head and neck cancer cases.” | 0.98 | phenotype_alias_lexicon_v2 |