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CXCL12 and multiple myeloma are reported together in 1 article.
Gene
CXCL12
- HGNC
- HGNC:10672
18articles
18mentions
0variants with confirmed gene link
Most co-reported phenotypes (articles)
Phenotype
Multiple myeloma
63articles
63mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Thymoquinone inhibits the CXCL12-induced chemotaxis of multiple myeloma cells and increases their susceptibility to Fas-mediated apoptosis.
PMID 21912642 | PMCID PMC3164673 | DOI 10.1371/journal.pone.0023741 · PloS one · 2011 · 5 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | CXCL12 | “Both cell lines strongly expressed CCR9, CXCR3 and CXCR4 chemokine receptors but only migrated toward CXCL12.” | 0.98 | hgnc_dict_v1 |
| phenotype | multiple myeloma | “Thymoquinone inhibits the CXCL12-induced chemotaxis of multiple myeloma cells and increases their susceptibility to Fas-mediated apoptosis.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | CCR9 | “Both cell lines strongly expressed CCR9, CXCR3 and CXCR4 chemokine receptors but only migrated toward CXCL12.” | 0.98 | hgnc_dict_v1 |
| gene | CXCR3 | “Both cell lines strongly expressed CCR9, CXCR3 and CXCR4 chemokine receptors but only migrated toward CXCL12.” | 0.98 | hgnc_dict_v1 |