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CYP11B2 and polycystic kidney disease are reported together in 1 article.
Gene
CYP11B2
- HGNC
- HGNC:2592
3articles
3mentions
3variants with confirmed gene link
Most co-reported phenotypes (articles)
Reported variants (articles · ClinVar status)
Phenotype
Polycystic kidney disease
66articles
66mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Aldosterone synthase gene is not a major susceptibility gene for progression of chronic kidney disease in patients with autosomal dominant polycystic kidney disease.
PMID 28540892 | DOI 10.4103/1319-2442.206464 · Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia · 2017 · 7 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | CYP11B2 | “The present study is aimed to investigate the potential modifier effect of CYP11B2 gene on the progression of CKD in ADPKD.” | 0.98 | hgnc_dict_v1 |
| phenotype | polycystic kidney disease | “Aldosterone synthase gene is not a major susceptibility gene for progression of chronic kidney disease in patients with autosomal dominant polycystic kidney disease.” | 0.98 | phenotype_alias_lexicon_v2 |
| phenotype | hypertension | “Hypertension is a frequent cause of chronic kidney disease (CKD) and mortality in patients with ADPKD.” | 0.98 | phenotype_alias_lexicon_v2 |
| phenotype | renal failure | “Aldosterone synthase gene is not a major susceptibility gene for progression of chronic kidney disease in patients with autosomal dominant polycystic kidney disease.” | 0.93 | phenotype_alias_lexicon_v2 |