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CYP1B1 and arrhythmia are reported together in 1 article.
Gene
CYP1B1
- HGNC
- HGNC:2597
58articles
58mentions
8variants with confirmed gene link
Most co-reported phenotypes (articles)
primary congenital glaucoma 30breast cancer 5diabetes mellitus 3hypertension 2arrhythmia 1autism spectrum disorder 1colorectal cancer 1coronary artery disease 1
Reported variants (articles · ClinVar status)
Phenotype
Arrhythmia
555articles
555mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Dasatinib induces gene expression of CYP1A1, CYP1B1, and cardiac hypertrophy markers (BNP, β-MHC) in rat cardiomyocyte H9c2 cells.
PMID 29975149 | DOI 10.1080/15376516.2018.1497746 · Toxicology mechanisms and methods · 2018 · 3 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | CYP1B1 | “Dasatinib induces gene expression of CYP1A1, CYP1B1, and cardiac hypertrophy markers (BNP, β-MHC) in rat cardiomyocyte H9c2 cells.” | 0.98 | hgnc_dict_v1 |
| phenotype | arrhythmia | “However, the dasatinib toxicity was reported as a side effect leading to arrhythmias and/or heart failure.” | 0.93 | phenotype_alias_lexicon_v2 |
| gene | CYP1A1 | “Dasatinib induces gene expression of CYP1A1, CYP1B1, and cardiac hypertrophy markers (BNP, β-MHC) in rat cardiomyocyte H9c2 cells.” | 0.98 | hgnc_dict_v1 |