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CYP1B1 and autism spectrum disorder are reported together in 1 article.
Gene
CYP1B1
- HGNC
- HGNC:2597
58articles
58mentions
8variants with confirmed gene link
Most co-reported phenotypes (articles)
primary congenital glaucoma 30breast cancer 5diabetes mellitus 3hypertension 2arrhythmia 1autism spectrum disorder 1colorectal cancer 1coronary artery disease 1
Reported variants (articles · ClinVar status)
Phenotype
Autism spectrum disorder
- HPO
- HP:0000729
881articles
881mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60In the search for reliable biomarkers for the early diagnosis of autism spectrum disorder: the role of vitamin D.
PMID 29497932 | DOI 10.1007/s11011-018-0199-1 · Metabolic brain disease · 2018 · 4 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | CYP1B1 | “There was found a relationship between autism severity on the CARS scale and the levels of 25(OH)D3 and CYP1B1.” | 0.98 | hgnc_dict_v1 |
| phenotype | autism spectrum disorder | “In the search for reliable biomarkers for the early diagnosis of autism spectrum disorder: the role of vitamin D.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | CYP2E1 | “High-sensitivity C-reactive protein (hs-CRP), cytochrome P450 2E1 (CYP2E1) and 8-hydroxy-2'-deoxyguanosine (8-OH-dG) are biomarkers related to inflammation and oxidative stress.” | 0.98 | hgnc_dict_v1 |
| population | Saudi Arabia | “In the present study, these biomarkers were together with serum 25-hydroxyvitamin D (25(OH)D3) analyzed in 28 (mean age seven years) Saudi male patients with ASD. The results of the ASD children were compared with 27 age and gender-matched neurotypical controls. The data indicated that Saudi patients with ASD have significantly lower plasma levels of 25(OH)D3 than neurotypical controls (38 ng/ml compared to 56 ng/ml, respectively; [P = 0.001]).” | 0.95 | saudi_context_rules_v1 |