Advanced search
Combine gene, variant, phenotype, region and year filters
Every result shows the extracted entities next to the sentences that support them; rows for the searched entities come first.
Transparent by designEvery result links extracted entities to its source sentence and publication identifier.
Knowledge-base search
About your search
EGF and atopic dermatitis are reported together in 1 article.
Gene
EGF
- HGNC
- HGNC:3229
15articles
15mentions
0variants with confirmed gene link
Most co-reported phenotypes (articles)
Phenotype
Atopic dermatitis
132articles
132mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Quantitative profiling of cytokines and chemokines in DOCK8-deficient and atopic dermatitis patients.
PMID 30252138 | DOI 10.1111/all.13610 · Allergy · 2019 · 4 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | EGF | “In contrast, epidermal growth factor (EGF) was significantly downregulated in a subgroup of DOCK8-deficient and AD patients, while IL-31 expression was comparable between both DOCK8-deficient and AD cohorts, possibly contributing toward pruritus seen in both groups.” | 0.98 | hgnc_dict_v1 |
| phenotype | atopic dermatitis | “Quantitative profiling of cytokines and chemokines in DOCK8-deficient and atopic dermatitis patients.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | DOCK8 | “Deficiency of DOCK8 protein is potentially a life-threatening autosomal recessive HIES and only curable with bone marrow transplantation.” | 0.98 | hgnc_dict_v1 |
| gene | CXCL10 | “RESULTS: CXCL10 and TNF-A were upregulated in DOCK8 patients when compared to AD, possibly contributing toward increased susceptibility to infections and cancer.” | 0.98 | hgnc_dict_v1 |