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Every result shows the extracted entities next to the sentences that support them; rows for the searched entities come first.
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EGF and breast cancer are reported together in 1 article.
Gene
EGF
- HGNC
- HGNC:3229
15articles
15mentions
0variants with confirmed gene link
Most co-reported phenotypes (articles)
Phenotype
Breast cancer
1,211articles
1,211mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60A review on epidermal growth factor receptor's role in breast and non-small cell lung cancer.
PMID 34742684 | DOI 10.1016/j.cbi.2021.109735 · Chemico-biological interactions · 2022 · 5 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | EGF | “Present study highlights the role and connectivity of EGF with various cancers via signaling pathways, cell surface receptors mechanism, macromolecules, mitochondrial genes and neoplasm.” | 0.98 | hgnc_dict_v1 |
| phenotype | breast cancer | “It belongs to the HER-2 receptor-family in breast cancer and responds best with anti-Herceptin therapy (anti-tyrosine kinase monoclonal antibody).” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | EGFR | “Epithelial growth factor receptor (EGFR) is a cell surface transmembrane receptor that mediates the tyrosine signaling pathway to carry the extracellular messages inside the cell and thereby alter the function of nucleus.” | 0.98 | hgnc_dict_v1 |
| gene | ERBB2 | “It is encoded by cell erythroblastosis virus oncogene B1, so called C-erb B1/ERBB2/HER-2 gene that acts as a proto-oncogene.” | 0.98 | hgnc_dict_v1 |