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EGF and hepatocellular carcinoma are reported together in 1 article.
Gene
EGF
- HGNC
- HGNC:3229
15articles
15mentions
0variants with confirmed gene link
Most co-reported phenotypes (articles)
Phenotype
Hepatocellular carcinoma
417articles
417mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Vitexin abrogates invasion and survival of hepatocellular carcinoma cells through targeting STAT3 signaling pathway.
PMID 32445654 | DOI 10.1016/j.biochi.2020.05.006 · Biochimie · 2020 · 5 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | EGF | “Vitexin downregulated DNA binding ability, reduced the nuclear pool of STAT3, and diminished epidermal growth factor (EGF)-driven STAT3 gene expression.” | 0.98 | hgnc_dict_v1 |
| phenotype | hepatocellular carcinoma | “Vitexin abrogates invasion and survival of hepatocellular carcinoma cells through targeting STAT3 signaling pathway.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | STAT3 | “Vitexin abrogates invasion and survival of hepatocellular carcinoma cells through targeting STAT3 signaling pathway.” | 0.98 | hgnc_dict_v1 |
| gene | JAK1 | “Vitexin effectively inhibited sustained activation of JAK1, JAK2, Src, and STAT3 in HCC cells.” | 0.98 | hgnc_dict_v1 |