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FGFR3 and multiple myeloma are reported together in 2 articles.
Gene
FGFR3
- HGNC
- HGNC:3690
24articles
24mentions
1variants with confirmed gene link
Most co-reported phenotypes (articles)
skeletal dysplasia 4multiple myeloma 2COVID-19 1breast cancer 1congenital cataract 1developmental delay 1hearing loss 1primary congenital glaucoma 1
Reported variants (articles · ClinVar status)
Phenotype
Multiple myeloma
63articles
63mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
2 records shown · first 60A diagnostic approach to detect cytogenetic heterogeneity and its prognostic significance in multiple myeloma.
PMID 37206191 | PMCID PMC10189271 | DOI 10.1016/j.jtumed.2023.03.009 · Journal of Taibah University Medical Sciences · 2023 · 4 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | FGFR3 | “METHODS: Bone marrow aspirates were obtained from 72 patients with MM and evaluated by conventional cytogenetics (CCs) and interphase fluorescence in situ hybridization (iFISH) techniques for a panel of probes, including immunoglobulin heavy chain (IgH)/CCND1, IgH/fibroblast growth factor receptor 3 (FGFR3), IgH/MAFB, 13q deletion, and deletion 17p.” | 0.98 | hgnc_dict_v1 |
| phenotype | multiple myeloma | “A diagnostic approach to detect cytogenetic heterogeneity and its prognostic significance in multiple myeloma.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | CCND1 | “METHODS: Bone marrow aspirates were obtained from 72 patients with MM and evaluated by conventional cytogenetics (CCs) and interphase fluorescence in situ hybridization (iFISH) techniques for a panel of probes, including immunoglobulin heavy chain (IgH)/CCND1, IgH/fibroblast growth factor receptor 3 (FGFR3), IgH/MAFB, 13q deletion, and deletion 17p.” | 0.98 | hgnc_dict_v1 |
| gene | MAFB | “METHODS: Bone marrow aspirates were obtained from 72 patients with MM and evaluated by conventional cytogenetics (CCs) and interphase fluorescence in situ hybridization (iFISH) techniques for a panel of probes, including immunoglobulin heavy chain (IgH)/CCND1, IgH/fibroblast growth factor receptor 3 (FGFR3), IgH/MAFB, 13q deletion, and deletion 17p.” | 0.98 | hgnc_dict_v1 |
Hypochondroplasia, Acanthosis Nigricans, and Insulin Resistance in a Child with FGFR3 Mutation: Is It Just an Association?
PMID 25505998 | PMCID PMC4255054 | DOI 10.1155/2014/840492 · Case reports in endocrinology · 2014 · 3 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | FGFR3 | “Hypochondroplasia, Acanthosis Nigricans, and Insulin Resistance in a Child with FGFR3 Mutation: Is It Just an Association?” | 0.98 | hgnc_dict_v1 |
| phenotype | multiple myeloma | “FGFR3 mutations cause wide spectrum of disorders ranging from skeletal dysplasias (hypochondroplasia, achondroplasia, and thanatophoric dysplasia), benign skin tumors (epidermal nevi, seborrhaeic keratosis, and acanthosis nigricans), and epithelial malignancies (multiple myeloma and prostate and bladder carcinoma).” | 0.98 | phenotype_alias_lexicon_v2 |
| phenotype | skeletal dysplasia | “Acanthosis nigricans might be seen in severe skeletal dysplasia, including thanatophoric dysplasia and SADDAN syndrome, without a biochemical evidence of hyperinsulinemia.” | 0.98 | phenotype_alias_lexicon_v2 |