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FOXO3 and ovarian cancer are reported together in 1 article.
Gene
FOXO3
- HGNC
- HGNC:3821
15articles
15mentions
3variants with confirmed gene link
Most co-reported phenotypes (articles)
breast cancer 2COVID-19 1MERS 1colorectal cancer 1diabetes mellitus 1hepatocellular carcinoma 1leukemia 1ovarian cancer 1
Reported variants (articles · ClinVar status)
Phenotype
Ovarian cancer
173articles
173mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Bisphenol A-induced oxidative stress increases the production of ovarian cancer stem cells in mice.
PMID 39322090 | DOI 10.1016/j.reprotox.2024.108724 · Reproductive toxicology (Elmsford, N.Y.) · 2024 · 6 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | FOXO3 | “The BPA administration also induces ROS production, which decreases the expression of antioxidant genes Superoxide dismutase 1 (SOD1), Superoxide dismutase 2 (SOD2), Catalase (CAT), Glutathione peroxidase 1 (GPX1), and Forkhead box O3 (FOXO3) in ovarian cells.” | 0.98 | hgnc_dict_v1 |
| phenotype | ovarian cancer | “Bisphenol A-induced oxidative stress increases the production of ovarian cancer stem cells in mice.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | CD44 | “The cancer stem cells (CSCs) in the ovaries were identified based on staining with anti-mouse CD44 and anti-mouse CD133 antibodies and analysed by flow cytometry.” | 0.98 | hgnc_dict_v1 |
| gene | SOD1 | “The BPA administration also induces ROS production, which decreases the expression of antioxidant genes Superoxide dismutase 1 (SOD1), Superoxide dismutase 2 (SOD2), Catalase (CAT), Glutathione peroxidase 1 (GPX1), and Forkhead box O3 (FOXO3) in ovarian cells.” | 0.98 | hgnc_dict_v1 |