Advanced search
Combine gene, variant, phenotype, region and year filters
Every result shows the extracted entities next to the sentences that support them; rows for the searched entities come first.
Transparent by designEvery result links extracted entities to its source sentence and publication identifier.
Knowledge-base search
About your search
GSK3B and prostate cancer are reported together in 3 articles.
Gene
GSK3B
- HGNC
- HGNC:4617
15articles
15mentions
0variants with confirmed gene link
Most co-reported phenotypes (articles)
Phenotype
Prostate cancer
218articles
218mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
3 records shown · first 60In silico identification of PPARγ agonists from diffractaic acid analogs in prostate cancer: a comprehensive computational approach.
PMID 40546399 | PMCID PMC12181459 | DOI 10.1007/s13205-025-04376-5 · 3 Biotech · 2025 · 18 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | GSK3B | “The KEGG enrichment analysis indicated that hsa05215: Prostate cancer is one of the most significant PCa enrichment signalling pathways which exhibited 18 protein-protein interactions including PDGFRB, PDGFRA, PPARG, GSK3B, MAP2K1, CREBBP, HSP90AA1, HSP90AB1, CHUK, PIK3CD, BRAF, PIK3CB, MTOR, AR, PIK3CA, PLAU, CDK2, and MAPK1.” | 0.98 | hgnc_dict_v1 |
| phenotype | prostate cancer | “In silico identification of PPARγ agonists from diffractaic acid analogs in prostate cancer: a comprehensive computational approach.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | PDGFRB | “The KEGG enrichment analysis indicated that hsa05215: Prostate cancer is one of the most significant PCa enrichment signalling pathways which exhibited 18 protein-protein interactions including PDGFRB, PDGFRA, PPARG, GSK3B, MAP2K1, CREBBP, HSP90AA1, HSP90AB1, CHUK, PIK3CD, BRAF, PIK3CB, MTOR, AR, PIK3CA, PLAU, CDK2, and MAPK1.” | 0.98 | hgnc_dict_v1 |
| gene | PDGFRA | “The KEGG enrichment analysis indicated that hsa05215: Prostate cancer is one of the most significant PCa enrichment signalling pathways which exhibited 18 protein-protein interactions including PDGFRB, PDGFRA, PPARG, GSK3B, MAP2K1, CREBBP, HSP90AA1, HSP90AB1, CHUK, PIK3CD, BRAF, PIK3CB, MTOR, AR, PIK3CA, PLAU, CDK2, and MAPK1.” | 0.98 | hgnc_dict_v1 |
A comparative mRNA- and miRNA transcriptomics reveals novel molecular signatures associated with metastatic prostate cancers.
PMID 36468011 | PMCID PMC9708707 | DOI 10.3389/fgene.2022.1066118 · Frontiers in genetics · 2022 · 9 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | GSK3B | “The subsequent miRNA-mRNA network and expression status analysis have helped us in narrowing down their number to 3 hub miRNAs (hsa-miR-455-3p, hsa-miR-548c-3p, and hsa-miR-582-5p) and 9 hub genes (NFIB, DICER1, GSK3B, DCAF7, FGFR1OP, ABHD2, NACC2, NR3C1, and FGF2).” | 0.98 | hgnc_dict_v1 |
| phenotype | prostate cancer | “Background: Prostate cancer (PC) is a fatally aggressive urogenital cancer killing millions of men, globally.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | NFIB | “The subsequent miRNA-mRNA network and expression status analysis have helped us in narrowing down their number to 3 hub miRNAs (hsa-miR-455-3p, hsa-miR-548c-3p, and hsa-miR-582-5p) and 9 hub genes (NFIB, DICER1, GSK3B, DCAF7, FGFR1OP, ABHD2, NACC2, NR3C1, and FGF2).” | 0.98 | hgnc_dict_v1 |
| gene | DICER1 | “The subsequent miRNA-mRNA network and expression status analysis have helped us in narrowing down their number to 3 hub miRNAs (hsa-miR-455-3p, hsa-miR-548c-3p, and hsa-miR-582-5p) and 9 hub genes (NFIB, DICER1, GSK3B, DCAF7, FGFR1OP, ABHD2, NACC2, NR3C1, and FGF2).” | 0.98 | hgnc_dict_v1 |
An Approach for Systems-Level Understanding of Prostate Cancer from High-Throughput Data Integration to Pathway Modeling and Simulation.
PMID 36552885 | PMCID PMC9777290 | DOI 10.3390/cells11244121 · Cells · 2022 · 6 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | GSK3B | “In terms of the pathways' components, GSK3B, YWHAE, HIF1A, ATP1A3, and PRKCA are shared between the aforementioned pathways and have higher connectivity with the pathways and the other pathway components.” | 0.98 | hgnc_dict_v1 |
| phenotype | prostate cancer | “An Approach for Systems-Level Understanding of Prostate Cancer from High-Throughput Data Integration to Pathway Modeling and Simulation.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | YWHAE | “In terms of the pathways' components, GSK3B, YWHAE, HIF1A, ATP1A3, and PRKCA are shared between the aforementioned pathways and have higher connectivity with the pathways and the other pathway components.” | 0.98 | hgnc_dict_v1 |
| gene | HIF1A | “In terms of the pathways' components, GSK3B, YWHAE, HIF1A, ATP1A3, and PRKCA are shared between the aforementioned pathways and have higher connectivity with the pathways and the other pathway components.” | 0.98 | hgnc_dict_v1 |