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GSTM1 and leukemia are reported together in 7 articles.
Gene
GSTM1
- HGNC
- HGNC:4632
46articles
46mentions
2variants with confirmed gene link
Most co-reported phenotypes (articles)
leukemia 7colorectal cancer 6diabetes mellitus 4hypertension 3obesity 3breast cancer 2asthma 1autism spectrum disorder 1
Reported variants (articles · ClinVar status)
Phenotype
Leukemia
652articles
652mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
7 records shown · first 60Impact of GSTT1 and GSTM1 Polymorphisms in the Susceptibility to Philadelphia Negative Chronic Myeloid Leukaemia.
PMID 36305131 | DOI 10.2174/1568009623666221027103845 · Current cancer drug targets · 2023 · 3 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | GSTM1 | “Impact of GSTT1 and GSTM1 Polymorphisms in the Susceptibility to Philadelphia Negative Chronic Myeloid Leukaemia.” | 0.98 | hgnc_dict_v1 |
| phenotype | leukemia | “Impact of GSTT1 and GSTM1 Polymorphisms in the Susceptibility to Philadelphia Negative Chronic Myeloid Leukaemia.” | 0.93 | phenotype_alias_lexicon_v2 |
| gene | GSTT1 | “Impact of GSTT1 and GSTM1 Polymorphisms in the Susceptibility to Philadelphia Negative Chronic Myeloid Leukaemia.” | 0.98 | hgnc_dict_v1 |
Increased Risk of Acute Lymphoblastic Leukemia in Adult Patients with GSTM1 Null Genetic Polymorphism.
PMID 35313604 | PMCID PMC8934168 | DOI 10.2147/PGPM.S356302 · Pharmacogenomics and personalized medicine · 2022 · 3 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | GSTM1 | “Increased Risk of Acute Lymphoblastic Leukemia in Adult Patients with GSTM1 Null Genetic Polymorphism.” | 0.98 | hgnc_dict_v1 |
| phenotype | leukemia | “Increased Risk of Acute Lymphoblastic Leukemia in Adult Patients with GSTM1 Null Genetic Polymorphism.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | GSTT1 | “PURPOSE: Glutathione S-transferases (GSTT1 and GSTM1) detoxify various endogenous and exogenous compounds and provide cytoprotective role against reactive species.” | 0.98 | hgnc_dict_v1 |
GSTT1 null and rs156697 Polymorphism in GSTO2 Influence the Risk and Therapeutic Outcome of B-Acute Lymphoblastic Leukemia Patients.
PMID 34722260 | PMCID PMC8552530 | DOI 10.3389/fonc.2021.714421 · Frontiers in oncology · 2021 · 8 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | GSTM1 | “GSTM1, GSTP1, and GSTO1 SNPs showed no significant association (p > 0.05).” | 0.98 | hgnc_dict_v1 |
| phenotype | leukemia | “GSTT1 null and rs156697 Polymorphism in GSTO2 Influence the Risk and Therapeutic Outcome of B-Acute Lymphoblastic Leukemia Patients.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | GSTT1 | “GSTT1 null and rs156697 Polymorphism in GSTO2 Influence the Risk and Therapeutic Outcome of B-Acute Lymphoblastic Leukemia Patients.” | 0.98 | hgnc_dict_v1 |
| gene | GSTO2 | “GSTT1 null and rs156697 Polymorphism in GSTO2 Influence the Risk and Therapeutic Outcome of B-Acute Lymphoblastic Leukemia Patients.” | 0.98 | hgnc_dict_v1 |
Combined GSTT1 Null, GSTM1 Null and XPD Lys/Lys Genetic Polymorphisms and Their Association with Increased Risk of Chronic Myeloid Leukemia.
PMID 34992428 | PMCID PMC8710912 | DOI 10.2147/PGPM.S342625 · Pharmacogenomics and personalized medicine · 2021 · 3 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | GSTM1 | “Combined GSTT1 Null, GSTM1 Null and XPD Lys/Lys Genetic Polymorphisms and Their Association with Increased Risk of Chronic Myeloid Leukemia.” | 0.98 | hgnc_dict_v1 |
| phenotype | leukemia | “Combined GSTT1 Null, GSTM1 Null and XPD Lys/Lys Genetic Polymorphisms and Their Association with Increased Risk of Chronic Myeloid Leukemia.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | GSTT1 | “Combined GSTT1 Null, GSTM1 Null and XPD Lys/Lys Genetic Polymorphisms and Their Association with Increased Risk of Chronic Myeloid Leukemia.” | 0.98 | hgnc_dict_v1 |
Genetic Polymorphism of GSTP1, GSTM1 and GSTT1 Genes and Susceptibility to Chronic Myeloid Leukaemia.
PMID 32102530 | PMCID PMC7332153 | DOI 10.31557/APJCP.2020.21.2.499 · Asian Pacific journal of cancer prevention : APJCP · 2020 · 4 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | GSTM1 | “Genetic Polymorphism of GSTP1, GSTM1 and GSTT1 Genes and Susceptibility to Chronic Myeloid Leukaemia.” | 0.98 | hgnc_dict_v1 |
| phenotype | leukemia | “Genetic Polymorphism of GSTP1, GSTM1 and GSTT1 Genes and Susceptibility to Chronic Myeloid Leukaemia.” | 0.93 | phenotype_alias_lexicon_v2 |
| gene | GSTP1 | “Genetic Polymorphism of GSTP1, GSTM1 and GSTT1 Genes and Susceptibility to Chronic Myeloid Leukaemia.” | 0.98 | hgnc_dict_v1 |
| gene | GSTT1 | “Genetic Polymorphism of GSTP1, GSTM1 and GSTT1 Genes and Susceptibility to Chronic Myeloid Leukaemia.” | 0.98 | hgnc_dict_v1 |
Genetic variants of glutathione S-transferase and the risk of acute myeloid leukemia in a Saudi population.
PMID 31762621 | PMCID PMC6864205 | DOI 10.1016/j.sjbs.2018.12.011 · Saudi journal of biological sciences · 2019 · 5 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | GSTM1 | “In the GST gene, GSTM1 and GSTT1 variants were genotyped by multiplex PCR, and GSTP1 variants were genotyped by PCR-RFLP analysis.” | 0.98 | hgnc_dict_v1 |
| phenotype | leukemia | “Genetic variants of glutathione S-transferase and the risk of acute myeloid leukemia in a Saudi population.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | GSTT1 | “In the GST gene, GSTM1 and GSTT1 variants were genotyped by multiplex PCR, and GSTP1 variants were genotyped by PCR-RFLP analysis.” | 0.98 | hgnc_dict_v1 |
| gene | GSTP1 | “In the GST gene, GSTM1 and GSTT1 variants were genotyped by multiplex PCR, and GSTP1 variants were genotyped by PCR-RFLP analysis.” | 0.98 | hgnc_dict_v1 |
Age- and gender-independent association of glutathione S-transferase null polymorphisms with chronic myeloid leukemia.
PMID 30995900 | PMCID PMC6868479 | DOI 10.17305/bjbms.2019.4176 · Bosnian journal of basic medical sciences · 2019 · 3 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | GSTM1 | “The aim of the current study is to investigate the association between GSTT1 and GSTM1 polymorphisms and chronic myeloid leukemia (CML) among Sudanese patients.” | 0.98 | hgnc_dict_v1 |
| phenotype | leukemia | “Age- and gender-independent association of glutathione S-transferase null polymorphisms with chronic myeloid leukemia.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | GSTT1 | “The aim of the current study is to investigate the association between GSTT1 and GSTM1 polymorphisms and chronic myeloid leukemia (CML) among Sudanese patients.” | 0.98 | hgnc_dict_v1 |