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GSTP1 and leukemia are reported together in 4 articles.
Gene
GSTP1
- HGNC
- HGNC:4638
30articles
30mentions
2variants with confirmed gene link
Most co-reported phenotypes (articles)
breast cancer 5colorectal cancer 5leukemia 4diabetes mellitus 2coronary artery disease 1hearing loss 1hepatocellular carcinoma 1lymphoma 1
Reported variants (articles · ClinVar status)
Phenotype
Leukemia
652articles
652mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
4 records shown · first 60GSTT1 null and rs156697 Polymorphism in GSTO2 Influence the Risk and Therapeutic Outcome of B-Acute Lymphoblastic Leukemia Patients.
PMID 34722260 | PMCID PMC8552530 | DOI 10.3389/fonc.2021.714421 · Frontiers in oncology · 2021 · 8 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | GSTP1 | “GSTM1, GSTP1, and GSTO1 SNPs showed no significant association (p > 0.05).” | 0.98 | hgnc_dict_v1 |
| phenotype | leukemia | “GSTT1 null and rs156697 Polymorphism in GSTO2 Influence the Risk and Therapeutic Outcome of B-Acute Lymphoblastic Leukemia Patients.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | GSTT1 | “GSTT1 null and rs156697 Polymorphism in GSTO2 Influence the Risk and Therapeutic Outcome of B-Acute Lymphoblastic Leukemia Patients.” | 0.98 | hgnc_dict_v1 |
| gene | GSTO2 | “GSTT1 null and rs156697 Polymorphism in GSTO2 Influence the Risk and Therapeutic Outcome of B-Acute Lymphoblastic Leukemia Patients.” | 0.98 | hgnc_dict_v1 |
Glutathione S-transferase gene polymorphic sequence variations: Association with risk and response to Imatinib among Chronic Myeloid Leukemia patients of Kashmir.
PMID 33470551 | DOI 10.1111/ijlh.13471 · International journal of laboratory hematology · 2021 · 5 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | GSTP1 | “GSTP1 variant genotypes AG (OR = 2.1, P = .003) and GG (OR = 5.6, P < .001), significantly associated with increased risk of CML.” | 0.98 | hgnc_dict_v1 |
| phenotype | leukemia | “Glutathione S-transferase gene polymorphic sequence variations: Association with risk and response to Imatinib among Chronic Myeloid Leukemia patients of Kashmir.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | GSTT1 | “RESULTS: GSTT1, GSTO1, and GSTO2 SNPs revealed no association, while as GSTM1null genotype was observed to protect against the development of CML (OR = 0.53, P = .01).” | 0.98 | hgnc_dict_v1 |
| gene | GSTO1 | “RESULTS: GSTT1, GSTO1, and GSTO2 SNPs revealed no association, while as GSTM1null genotype was observed to protect against the development of CML (OR = 0.53, P = .01).” | 0.98 | hgnc_dict_v1 |
Genetic Polymorphism of GSTP1, GSTM1 and GSTT1 Genes and Susceptibility to Chronic Myeloid Leukaemia.
PMID 32102530 | PMCID PMC7332153 | DOI 10.31557/APJCP.2020.21.2.499 · Asian Pacific journal of cancer prevention : APJCP · 2020 · 4 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | GSTP1 | “Genetic Polymorphism of GSTP1, GSTM1 and GSTT1 Genes and Susceptibility to Chronic Myeloid Leukaemia.” | 0.98 | hgnc_dict_v1 |
| phenotype | leukemia | “Genetic Polymorphism of GSTP1, GSTM1 and GSTT1 Genes and Susceptibility to Chronic Myeloid Leukaemia.” | 0.93 | phenotype_alias_lexicon_v2 |
| gene | GSTM1 | “Genetic Polymorphism of GSTP1, GSTM1 and GSTT1 Genes and Susceptibility to Chronic Myeloid Leukaemia.” | 0.98 | hgnc_dict_v1 |
| gene | GSTT1 | “Genetic Polymorphism of GSTP1, GSTM1 and GSTT1 Genes and Susceptibility to Chronic Myeloid Leukaemia.” | 0.98 | hgnc_dict_v1 |
Genetic variants of glutathione S-transferase and the risk of acute myeloid leukemia in a Saudi population.
PMID 31762621 | PMCID PMC6864205 | DOI 10.1016/j.sjbs.2018.12.011 · Saudi journal of biological sciences · 2019 · 5 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | GSTP1 | “In the GST gene, GSTM1 and GSTT1 variants were genotyped by multiplex PCR, and GSTP1 variants were genotyped by PCR-RFLP analysis.” | 0.98 | hgnc_dict_v1 |
| phenotype | leukemia | “Genetic variants of glutathione S-transferase and the risk of acute myeloid leukemia in a Saudi population.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | GSTM1 | “In the GST gene, GSTM1 and GSTT1 variants were genotyped by multiplex PCR, and GSTP1 variants were genotyped by PCR-RFLP analysis.” | 0.98 | hgnc_dict_v1 |
| gene | GSTT1 | “In the GST gene, GSTM1 and GSTT1 variants were genotyped by multiplex PCR, and GSTP1 variants were genotyped by PCR-RFLP analysis.” | 0.98 | hgnc_dict_v1 |