Advanced search
Combine gene, variant, phenotype, region and year filters
Every result shows the extracted entities next to the sentences that support them; rows for the searched entities come first.
Transparent by designEvery result links extracted entities to its source sentence and publication identifier.
Knowledge-base search
About your search
GSTT1 and hypertension are reported together in 4 articles.
Gene
GSTT1
- HGNC
- HGNC:4641
39articles
39mentions
0variants with confirmed gene link
Most co-reported phenotypes (articles)
Phenotype
Hypertension
828articles
828mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
4 records shown · first 60Association of Genetic and Allelic Variants of Von Willebrand Factor (VWF), Glutathione S-Transferase and Tumor Necrosis Factor Alpha with Ischemic Stroke Susceptibility and Progression in the Saudi Population.
PMID 37240845 | PMCID PMC10224221 | DOI 10.3390/life13051200 · Life (Basel, Switzerland) · 2023 · 11 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | GSTT1 | “The incidence of ischemic stroke is probably increased by the interaction of GSTT1 and GSTM1 null genotypes with high blood pressure, diabetes and cigarette smoking.” | 0.98 | hgnc_dict_v1 |
| phenotype | hypertension | “The incidence of ischemic stroke is probably increased by the interaction of GSTT1 and GSTM1 null genotypes with high blood pressure, diabetes and cigarette smoking.” | 0.93 | phenotype_alias_lexicon_v2 |
| gene | VWF | “Association of Genetic and Allelic Variants of Von Willebrand Factor (VWF), Glutathione S-Transferase and Tumor Necrosis Factor Alpha with Ischemic Stroke Susceptibility and Progression in the Saudi Population.” | 0.98 | hgnc_dict_v1 |
| gene | GSTM1 | “The incidence of ischemic stroke is probably increased by the interaction of GSTT1 and GSTM1 null genotypes with high blood pressure, diabetes and cigarette smoking.” | 0.98 | hgnc_dict_v1 |
Machine learning algorithm-based risk prediction model of coronary artery disease.
PMID 29995270 | DOI 10.1007/s11033-018-4236-2 · Molecular biology reports · 2018 · 6 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | GSTT1 | “This model depicted hypertension and alcohol intake as the key predictors of CAD risk followed by cSHMT C1420T, GCPII C1561T, diabetes, GSTT1, CYP1A1 m2, TYMs 5'-UTR 28 bp tandem repeat and MTRR A66G.” | 0.98 | hgnc_dict_v1 |
| phenotype | hypertension | “This model depicted hypertension and alcohol intake as the key predictors of CAD risk followed by cSHMT C1420T, GCPII C1561T, diabetes, GSTT1, CYP1A1 m2, TYMs 5'-UTR 28 bp tandem repeat and MTRR A66G.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | CYP1A1 | “This model depicted hypertension and alcohol intake as the key predictors of CAD risk followed by cSHMT C1420T, GCPII C1561T, diabetes, GSTT1, CYP1A1 m2, TYMs 5'-UTR 28 bp tandem repeat and MTRR A66G.” | 0.98 | hgnc_dict_v1 |
| gene | MTRR | “This model depicted hypertension and alcohol intake as the key predictors of CAD risk followed by cSHMT C1420T, GCPII C1561T, diabetes, GSTT1, CYP1A1 m2, TYMs 5'-UTR 28 bp tandem repeat and MTRR A66G.” | 0.98 | hgnc_dict_v1 |
Association of glutathione S-transferase GSTM1 and GSTT1 deletion polymorphisms with obesity and their relationship with body mass index, lipoprotein and hypertension among young age Saudis.
PMID 27721975 | PMCID PMC5036254 | DOI 10.1177/2048004016669645 · JRSM cardiovascular disease · 2016 · 5 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | GSTT1 | “Association of glutathione S-transferase GSTM1 and GSTT1 deletion polymorphisms with obesity and their relationship with body mass index, lipoprotein and hypertension among young age Saudis.” | 0.98 | hgnc_dict_v1 |
| phenotype | hypertension | “Association of glutathione S-transferase GSTM1 and GSTT1 deletion polymorphisms with obesity and their relationship with body mass index, lipoprotein and hypertension among young age Saudis.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | GSTM1 | “Association of glutathione S-transferase GSTM1 and GSTT1 deletion polymorphisms with obesity and their relationship with body mass index, lipoprotein and hypertension among young age Saudis.” | 0.98 | hgnc_dict_v1 |
| phenotype | obesity | “Association of glutathione S-transferase GSTM1 and GSTT1 deletion polymorphisms with obesity and their relationship with body mass index, lipoprotein and hypertension among young age Saudis.” | 0.98 | phenotype_alias_lexicon_v2 |
T null and M null genotypes of the glutathione S-transferase gene are risk factor for CAD independent of smoking.
PMID 16620396 | PMCID PMC1458325 | DOI 10.1186/1471-2350-7-38 · BMC medical genetics · 2006 · 9 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | GSTT1 | “BACKGROUND: The association of the deletion in GSTT1 and GSTM1 genes with coronary artery disease (CAD) among smokers is controversial.” | 0.98 | hgnc_dict_v1 |
| phenotype | hypertension | “Univariate analysis also showed that smoking, age, hypercholesterolemia and hypertriglyceridemia, diabetes mellitus, family history of CAD, hypertension and obesity are all associated with CAD, whereas gender and myocardial infarction are not.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | GSTM1 | “BACKGROUND: The association of the deletion in GSTT1 and GSTM1 genes with coronary artery disease (CAD) among smokers is controversial.” | 0.98 | hgnc_dict_v1 |
| phenotype | myocardial infarction | “Univariate analysis also showed that smoking, age, hypercholesterolemia and hypertriglyceridemia, diabetes mellitus, family history of CAD, hypertension and obesity are all associated with CAD, whereas gender and myocardial infarction are not.” | 0.98 | phenotype_alias_lexicon_v2 |