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HLA-DQA1 and systemic lupus erythematosus are reported together in 2 articles.
Gene
HLA-DQA1
- HGNC
- HGNC:4942
9articles
9mentions
2variants with confirmed gene link
Most co-reported phenotypes (articles)
diabetes mellitus 3celiac disease 2systemic lupus erythematosus 2hepatitis B 1hepatocellular carcinoma 1multiple sclerosis 1nephrotic syndrome 1rheumatoid arthritis 1
Reported variants (articles · ClinVar status)
Phenotype
Systemic lupus erythematosus
191articles
191mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
2 records shown · first 60Exploring the role of genetic variants in susceptibility to autoimmune Diseases: A molecular genetics approach.
PMID 41237580 | DOI 10.1016/j.humimm.2025.111614 · Human immunology · 2025 · 12 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | HLA-DQA1 | “This study identifies several significant genetic variants associated with autoimmune diseases, including PTPN22, HLA-DRB1, HLA-DQA1, IRF5, IL10, and other immune-regulatory genes.” | 0.98 | hgnc_dict_v1 |
| phenotype | systemic lupus erythematosus | “The purpose of this study is to identify key genetic variants associated with rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, and type 1 diabetes, and to investigate how these variants interact with environmental exposures to influence risk and age of onset.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | PTPN22 | “This study identifies several significant genetic variants associated with autoimmune diseases, including PTPN22, HLA-DRB1, HLA-DQA1, IRF5, IL10, and other immune-regulatory genes.” | 0.98 | hgnc_dict_v1 |
| gene | HLA-DRB1 | “This study identifies several significant genetic variants associated with autoimmune diseases, including PTPN22, HLA-DRB1, HLA-DQA1, IRF5, IL10, and other immune-regulatory genes.” | 0.98 | hgnc_dict_v1 |
The involvement of HLA -DRB1*, DQA1*, DQB1* and complement C4A loci in diagnosing systemic lupus erythematosus among Tunisians.
PMID 15310011 | PMCID PMC6147822 | DOI 10.5144/0256-4947.2004.31 · Annals of Saudi medicine · 2004 · 5 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | HLA-DQA1 | “HLA-DQA1*0102 and DQA1*0501 were significantly increased in the SLE patients.” | 0.98 | hgnc_dict_v1 |
| phenotype | systemic lupus erythematosus | “The involvement of HLA -DRB1*, DQA1*, DQB1* and complement C4A loci in diagnosing systemic lupus erythematosus among Tunisians.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | C4A | “The involvement of HLA -DRB1*, DQA1*, DQB1* and complement C4A loci in diagnosing systemic lupus erythematosus among Tunisians.” | 0.98 | hgnc_dict_v1 |
| gene | HLA-DRB1 | “PATIENTS AND METHODS: We compared HLA-DRB1*, DQA1, DQB1* and C4 allotypes in 62 Tunisian SLE patients and 100 matched controls.” | 0.98 | hgnc_dict_v1 |