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HLA-DQB1 and renal failure are reported together in 1 article.
Gene
HLA-DQB1
- HGNC
- HGNC:4944
40articles
40mentions
1variants with confirmed gene link
Most co-reported phenotypes (articles)
diabetes mellitus 7celiac disease 3COVID-19 2systemic lupus erythematosus 2MERS 1asthma 1multiple sclerosis 1nephrotic syndrome 1
Reported variants (articles · ClinVar status)
Phenotype
Renal failure
523articles
523mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Human leucocyte antigens: their association with end-stage renal disease in Saudi patients awaiting transplantation.
PMID 23304791 · British journal of biomedical science · 2012 · 4 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | HLA-DQB1 | “No significant differences were observed between the two groups in respect of HLA-A2, HLA-B50(21), HLA-B51(5) and HLA-Cw7 (HLA Class I), and HLA-DRB1*04, HLA-DRB1*07 and HLA-DQB1*02 (HLA Class II).” | 0.98 | hgnc_dict_v1 |
| phenotype | renal failure | “Human leucocyte antigens: their association with end-stage renal disease in Saudi patients awaiting transplantation.” | 0.93 | phenotype_alias_lexicon_v2 |
| gene | HLA-DRB1 | “No significant differences were observed between the two groups in respect of HLA-A2, HLA-B50(21), HLA-B51(5) and HLA-Cw7 (HLA Class I), and HLA-DRB1*04, HLA-DRB1*07 and HLA-DQB1*02 (HLA Class II).” | 0.98 | hgnc_dict_v1 |
| population | Saudi Arabia | “Human leucocyte antigens: their association with end-stage renal disease in Saudi patients awaiting transplantation. Genotyping data (HLA) obtained between 2005 and 2009 on 235 unrelated Saudi patients (147 males, 88 females; mean age: 58 +/- 7 years) with ESRD awaiting renal transplantation were assessed retrospectively at the King Khalid University Hospital. Data were compared with the results on 60 normal, healthy, unrelated Saudi individuals (37 males and 23 females; mean age: 51 +/- 5 years).” | 0.95 | saudi_context_rules_v1 |