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HLA-DQB1 and rheumatoid arthritis are reported together in 1 article.
Gene
HLA-DQB1
- HGNC
- HGNC:4944
40articles
40mentions
1variants with confirmed gene link
Most co-reported phenotypes (articles)
diabetes mellitus 7celiac disease 3COVID-19 2systemic lupus erythematosus 2MERS 1asthma 1multiple sclerosis 1nephrotic syndrome 1
Reported variants (articles · ClinVar status)
Phenotype
Rheumatoid arthritis
212articles
212mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Association of Human Leukocyte Antigen (HLA) class II (DRB1 and DQB1) alleles and haplotypes with Rheumatoid Arthritis in Sudanese patients.
PMID 37426636 | PMCID PMC10324672 | DOI 10.3389/fimmu.2023.1178546 · Frontiers in immunology · 2023 · 3 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | HLA-DQB1 | “Moreover, the HLA-DQB1*03 allele was strongly associated with RA risk (42.2%, P = 2.2x10-8), whereas, HLA-DQB1*02 and *06 showed protective effects against RA (23.1% and 42.2%, P = 0.024 and P = 2.2x10-6, respectively).” | 0.98 | hgnc_dict_v1 |
| phenotype | rheumatoid arthritis | “Association of Human Leukocyte Antigen (HLA) class II (DRB1 and DQB1) alleles and haplotypes with Rheumatoid Arthritis in Sudanese patients.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | HLA-DRB1 | “The frequency of HLA-DRB1 and -DQB1 alleles and DRB1-DQB1 haplotypes were determined in 122 RA patients and 100 controls.” | 0.98 | hgnc_dict_v1 |