Advanced search
Combine gene, variant, phenotype, region and year filters
Every result shows the extracted entities next to the sentences that support them; rows for the searched entities come first.
Transparent by designEvery result links extracted entities to its source sentence and publication identifier.
Knowledge-base search
About your search
HSP90AA1 and lung cancer are reported together in 4 articles.
Gene
HSP90AA1
- HGNC
- HGNC:5253
21articles
21mentions
0variants with confirmed gene link
Most co-reported phenotypes (articles)
Phenotype
Lung cancer
398articles
398mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
4 records shown · first 60Deciphering the Anticancer Arsenal of Piper longum: Network Pharmacology and Molecular Docking Unveil Phytochemical Targets Against Lung Cancer.
PMID 39113883 | PMCID PMC11302554 | DOI 10.7150/ijms.98393 · International journal of medical sciences · 2024 · 6 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | HSP90AA1 | “Notably, our findings reaffirm the relevance of lung cancer genes, such as CTNNB1, STAT3, HIF1A, HSP90AA1, and ERBB2, integral to various cellular processes and pivotal in cancer genesis and advancement.” | 0.98 | hgnc_dict_v1 |
| phenotype | lung cancer | “Deciphering the Anticancer Arsenal of Piper longum: Network Pharmacology and Molecular Docking Unveil Phytochemical Targets Against Lung Cancer.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | CTNNB1 | “Notably, our findings reaffirm the relevance of lung cancer genes, such as CTNNB1, STAT3, HIF1A, HSP90AA1, and ERBB2, integral to various cellular processes and pivotal in cancer genesis and advancement.” | 0.98 | hgnc_dict_v1 |
| gene | STAT3 | “Notably, our findings reaffirm the relevance of lung cancer genes, such as CTNNB1, STAT3, HIF1A, HSP90AA1, and ERBB2, integral to various cellular processes and pivotal in cancer genesis and advancement.” | 0.98 | hgnc_dict_v1 |
Multi-targeted effects of D-carvone against Non-Small Cell Lung Cancer (NSCLC): A network pharmacology-based study.
PMID 38795847 | DOI 10.1016/j.taap.2024.116978 · Toxicology and applied pharmacology · 2024 · 5 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | HSP90AA1 | “Further analysis identified 5 core/ hub targets of CN including JAK2, ERK1, ESR1, GSK3B and HSP90AA1.” | 0.98 | hgnc_dict_v1 |
| phenotype | lung cancer | “Multi-targeted effects of D-carvone against Non-Small Cell Lung Cancer (NSCLC): A network pharmacology-based study.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | JAK2 | “Further analysis identified 5 core/ hub targets of CN including JAK2, ERK1, ESR1, GSK3B and HSP90AA1.” | 0.98 | hgnc_dict_v1 |
| gene | ESR1 | “Further analysis identified 5 core/ hub targets of CN including JAK2, ERK1, ESR1, GSK3B and HSP90AA1.” | 0.98 | hgnc_dict_v1 |
CDK1 and HSP90AA1 Appear as the Novel Regulatory Genes in Non-Small Cell Lung Cancer: A Bioinformatics Approach.
PMID 35330393 | PMCID PMC8955443 | DOI 10.3390/jpm12030393 · Journal of personalized medicine · 2022 · 4 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | HSP90AA1 | “CDK1 and HSP90AA1 Appear as the Novel Regulatory Genes in Non-Small Cell Lung Cancer: A Bioinformatics Approach.” | 0.98 | hgnc_dict_v1 |
| phenotype | lung cancer | “CDK1 and HSP90AA1 Appear as the Novel Regulatory Genes in Non-Small Cell Lung Cancer: A Bioinformatics Approach.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | CDK1 | “CDK1 and HSP90AA1 Appear as the Novel Regulatory Genes in Non-Small Cell Lung Cancer: A Bioinformatics Approach.” | 0.98 | hgnc_dict_v1 |
| gene | MCC | “From the PPI network, top ten genes of each of the six topological properties like closeness centrality, maximal clique centrality (MCC), Maximum Neighborhood Component (MNC), radiality, EPC (Edge Percolated Component) and bottleneck were considered for key regulator identification.” | 0.98 | hgnc_dict_v1 |
An in silico analytical study of lung cancer and smokers datasets from gene expression omnibus (GEO) for prediction of differentially expressed genes.
PMID 26124566 | PMCID PMC4464538 | DOI 10.6026/97320630011229 · Bioinformation · 2015 · 5 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | HSP90AA1 | “GPR110, IL1RN and HSP90AA1 were found directly associated with lung cancer.” | 0.98 | hgnc_dict_v1 |
| phenotype | lung cancer | “An in silico analytical study of lung cancer and smokers datasets from gene expression omnibus (GEO) for prediction of differentially expressed genes.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | IL1RN | “GPR110, IL1RN and HSP90AA1 were found directly associated with lung cancer.” | 0.98 | hgnc_dict_v1 |
| gene | SEMA6A | “SEMA6A differentially expresses in only non-smoking lung cancer samples.” | 0.98 | hgnc_dict_v1 |