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IL10 and Crohn disease are reported together in 2 articles.
Gene
IL10
- HGNC
- HGNC:5962
39articles
39mentions
5variants with confirmed gene link
Most co-reported phenotypes (articles)
diabetes mellitus 6inflammatory bowel disease 3ulcerative colitis 3COVID-19 2Crohn disease 2dyslipidemia 2rheumatoid arthritis 2hepatitis C 1
Reported variants (articles · ClinVar status)
Phenotype
Crohn disease
435articles
435mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
2 records shown · first 60High-Throughput Whole-Exome Sequencing and Large-Scale Computational Analysis to Identify the Genetic Biomarkers to Predict the Vedolizumab Response Status in Inflammatory Bowel Disease Patients from Saudi Arabia.
PMID 40002872 | PMCID PMC11852680 | DOI 10.3390/biomedicines13020459 · Biomedicines · 2025 · 12 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | IL10 | “The rare variant analysis prioritized NOD2, IL23, IL10, IL27, and TRAF1 genes in non-responders.” | 0.98 | hgnc_dict_v1 |
| phenotype | Crohn disease | “Methods: A cohort of 16 patients with IBD, including 4 with Crohn's disease and 12 with ulcerative colitis, were recruited.” | 0.93 | phenotype_alias_lexicon_v2 |
| gene | NOD2 | “The rare variant analysis prioritized NOD2, IL23, IL10, IL27, and TRAF1 genes in non-responders.” | 0.98 | hgnc_dict_v1 |
| gene | IL27 | “The rare variant analysis prioritized NOD2, IL23, IL10, IL27, and TRAF1 genes in non-responders.” | 0.98 | hgnc_dict_v1 |
Current concepts in pediatric inflammatory bowel disease; IL10/IL10R colitis as a model disease.
PMID 31304220 | PMCID PMC6603158 | DOI 10.1016/j.ijpam.2019.02.002 · International journal of pediatrics & adolescent medicine · 2019 · 5 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | IL10 | “Current concepts in pediatric inflammatory bowel disease; IL10/IL10R colitis as a model disease.” | 0.98 | hgnc_dict_v1 |
| phenotype | Crohn disease | “Inflammatory bowel disease (IBD) is a heterogeneous group of disorders composed mainly of ulcerative colitis (UC) and Crohn's disease (CD) and undetermined IBD.” | 0.93 | phenotype_alias_lexicon_v2 |
| phenotype | inflammatory bowel disease | “Current concepts in pediatric inflammatory bowel disease; IL10/IL10R colitis as a model disease.” | 0.98 | phenotype_alias_lexicon_v2 |
| phenotype | ulcerative colitis | “Inflammatory bowel disease (IBD) is a heterogeneous group of disorders composed mainly of ulcerative colitis (UC) and Crohn's disease (CD) and undetermined IBD.” | 0.98 | phenotype_alias_lexicon_v2 |