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IMPACT and atopic dermatitis are reported together in 2 articles.
Gene
IMPACT
- HGNC
- HGNC:20387
39articles
39mentions
0variants with confirmed gene link
Most co-reported phenotypes (articles)
Phenotype
Atopic dermatitis
132articles
132mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
2 records shown · first 60Association of Genetic Liability to Allergic Diseases with Overall and Early-Onset Colorectal Cancer Risk: A Mendelian Randomization Study.
PMID 39982694 | PMCID PMC12046324 | DOI 10.1158/1055-9965.EPI-24-0970 · Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025 · 5 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | IMPACT | “IMPACT: Our results provide evidence that allergic responses may also have a role in immunosurveillance against colorectal cancer.” | 0.98 | hgnc_dict_v1 |
| phenotype | atopic dermatitis | “METHODS: Genome-wide association study summary statistical data were used to identify genetic variants associated with allergic diseases (Nvariants = 65) and individual allergic conditions (asthma, hay fever/allergic rhinitis, and eczema).” | 0.93 | phenotype_alias_lexicon_v2 |
| phenotype | colorectal cancer | “Association of Genetic Liability to Allergic Diseases with Overall and Early-Onset Colorectal Cancer Risk: A Mendelian Randomization Study.” | 0.98 | phenotype_alias_lexicon_v2 |
| phenotype | asthma | “METHODS: Genome-wide association study summary statistical data were used to identify genetic variants associated with allergic diseases (Nvariants = 65) and individual allergic conditions (asthma, hay fever/allergic rhinitis, and eczema).” | 0.98 | phenotype_alias_lexicon_v2 |
Examining the association between autism spectrum disorder and atopic eczema: meta-analysis of current evidence.
PMID 39128926 | DOI 10.1038/s41390-024-03456-1 · Pediatric research · 2025 · 3 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | IMPACT | “IMPACT: Our study conducted a meta-analysis on the association between autism spectrum disorder (ASD) and atopic eczema (AE), shedding light on potential associations and underlying mechanisms.” | 0.98 | hgnc_dict_v1 |
| phenotype | atopic dermatitis | “Examining the association between autism spectrum disorder and atopic eczema: meta-analysis of current evidence.” | 0.93 | phenotype_alias_lexicon_v2 |
| phenotype | autism spectrum disorder | “Examining the association between autism spectrum disorder and atopic eczema: meta-analysis of current evidence.” | 0.98 | phenotype_alias_lexicon_v2 |