Advanced search
Combine gene, variant, phenotype, region and year filters
Every result shows the extracted entities next to the sentences that support them; rows for the searched entities come first.
Transparent by designEvery result links extracted entities to its source sentence and publication identifier.
Knowledge-base search
About your search
KRAS and hepatocellular carcinoma are reported together in 1 article.
Gene
KRAS
- HGNC
- HGNC:6407
119articles
119mentions
2variants with confirmed gene link
Most co-reported phenotypes (articles)
colorectal cancer 41lung cancer 19thyroid cancer 10breast cancer 5lymphoma 3diabetes mellitus 2leukemia 2cardiomyopathy 1
Reported variants (articles · ClinVar status)
Phenotype
Hepatocellular carcinoma
417articles
417mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60IQGAP1 gene silencing induces apoptosis and decreases the invasive capacity of human hepatocellular carcinoma cells.
PMID 27488117 | DOI 10.1007/s13277-016-5283-8 · Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016 · 11 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | KRAS | “Furthermore, we observed that the mRNA levels of HRAS, KRAS, NRAS, and MRAS decreased upon IQGAP1 silencing.” | 0.98 | hgnc_dict_v1 |
| phenotype | hepatocellular carcinoma | “IQGAP1 gene silencing induces apoptosis and decreases the invasive capacity of human hepatocellular carcinoma cells.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | IQGAP1 | “IQGAP1 gene silencing induces apoptosis and decreases the invasive capacity of human hepatocellular carcinoma cells.” | 0.98 | hgnc_dict_v1 |
| gene | IQGAP2 | “IQGAP1 is expressed in all cells, while IQGAP2 and IQGAP3 are mainly expressed in hepatic cells.” | 0.98 | hgnc_dict_v1 |