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LRP1 and diabetes mellitus are reported together in 1 article.
Gene
LRP1
- HGNC
- HGNC:6692
8articles
8mentions
1variants with confirmed gene link
Most co-reported phenotypes (articles)
Alzheimer disease 3Marfan syndrome 1Parkinson disease 1congenital heart disease 1coronary artery disease 1diabetes mellitus 1epilepsy 1
Reported variants (articles · ClinVar status)
Phenotype
Diabetes mellitus
2,156articles
2,156mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease.
PMID 28209224 | PMCID PMC5314135 | DOI 10.1016/j.jacc.2016.11.056 · Journal of the American College of Cardiology · 2017 · 5 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | LRP1 | “RESULTS: We identified 6 new loci associated with CAD at genome-wide significance: on 2q37 (KCNJ13-GIGYF2), 6p21 (C2), 11p15 (MRVI1-CTR9), 12q13 (LRP1), 12q24 (SCARB1), and 16q13 (CETP).” | 0.98 | hgnc_dict_v1 |
| phenotype | diabetes mellitus | “To evaluate pleiotropy, we tested CAD loci for association with cardiovascular risk factors (lipid traits, blood pressure phenotypes, body mass index, diabetes, and smoking behavior), as well as with other diseases/traits through interrogation of currently available genome-wide association study catalogs.” | 0.93 | phenotype_alias_lexicon_v2 |
| gene | SCARB1 | “RESULTS: We identified 6 new loci associated with CAD at genome-wide significance: on 2q37 (KCNJ13-GIGYF2), 6p21 (C2), 11p15 (MRVI1-CTR9), 12q13 (LRP1), 12q24 (SCARB1), and 16q13 (CETP).” | 0.98 | hgnc_dict_v1 |
| gene | CETP | “RESULTS: We identified 6 new loci associated with CAD at genome-wide significance: on 2q37 (KCNJ13-GIGYF2), 6p21 (C2), 11p15 (MRVI1-CTR9), 12q13 (LRP1), 12q24 (SCARB1), and 16q13 (CETP).” | 0.98 | hgnc_dict_v1 |