Advanced search
Combine gene, variant, phenotype, region and year filters
Every result shows the extracted entities next to the sentences that support them; rows for the searched entities come first.
Transparent by designEvery result links extracted entities to its source sentence and publication identifier.
Knowledge-base search
About your search
LRP5 and myocardial infarction are reported together in 1 article.
Gene
LRP5
- HGNC
- HGNC:6697
6articles
6mentions
1variants with confirmed gene link
Most co-reported phenotypes (articles)
Reported variants (articles · ClinVar status)
Phenotype
Myocardial infarction
274articles
274mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60LRP5: A Multifaceted Co-Receptor in Development, Disease, and Therapeutic Target.
PMID 40940800 | PMCID PMC12427940 | DOI 10.3390/cells14171391 · Cells · 2025 · 3 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | LRP5 | “LRP5: A Multifaceted Co-Receptor in Development, Disease, and Therapeutic Target.” | 0.98 | hgnc_dict_v1 |
| phenotype | myocardial infarction | “Although it plays a protective role in acute injuries such as myocardial infarction and acute kidney injury, LRP5 also contributes to chronic pathologies such as tubulointerstitial fibrosis, polycystic kidney disease, and atherosclerosis through fibrotic and inflammatory pathways.” | 0.98 | phenotype_alias_lexicon_v2 |
| phenotype | polycystic kidney disease | “Although it plays a protective role in acute injuries such as myocardial infarction and acute kidney injury, LRP5 also contributes to chronic pathologies such as tubulointerstitial fibrosis, polycystic kidney disease, and atherosclerosis through fibrotic and inflammatory pathways.” | 0.98 | phenotype_alias_lexicon_v2 |