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MALAT1 and gastric cancer are reported together in 2 articles.
Gene
MALAT1
- HGNC
- HGNC:29665
32articles
32mentions
2variants with confirmed gene link
Most co-reported phenotypes (articles)
diabetes mellitus 4breast cancer 2colorectal cancer 2gastric cancer 2hypertension 2lung cancer 2systemic lupus erythematosus 2Crohn disease 1
Reported variants (articles · ClinVar status)
Phenotype
Gastric cancer
106articles
106mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
2 records shown · first 60P53-associated lncRNAs regulate immune functions and RNA-modifiers in gastric cancer.
PMID 39166030 | PMCID PMC11334848 | DOI 10.1016/j.heliyon.2024.e35228 · Heliyon · 2024 · 13 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | MALAT1 | “Additionally, we found that high expression of GAS5 and low expression of MALAT1 in Helicobacter pylori (H-pylori) positive GC patients.” | 0.98 | hgnc_dict_v1 |
| phenotype | gastric cancer | “P53-associated lncRNAs regulate immune functions and RNA-modifiers in gastric cancer.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | TP53 | “TP53, a guardian of the genome, suppresses or enhances tumors through various regulatory pathways.” | 0.98 | hgnc_dict_v1 |
| gene | ZC3H13 | “Similarly, significant differences in immune function (APC_co_stimulation, CCR, and checkpoint) and m6A modification (FTO, ZC3H13, YTHDC1, and RBM15), and m5C modification (NOP2 and TET1) between both groups were also observed.” | 0.98 | hgnc_dict_v1 |
Comprehensive analysis of aberrantly expressed lncRNAs and construction of ceRNA network in gastric cancer.
PMID 29719612 | PMCID PMC5915079 | DOI 10.18632/oncotarget.24841 · Oncotarget · 2018 · 7 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | MALAT1 | “The ceRNA network analysis revealed that the differentially regulated miR-21 and miR-148a were playing as central candidates coordinating sponging activity of the lncRNAs analyzed (H19, TUG1 and MALAT1) in this study and the overexpression of H19 and miR-21 could be a signature event of gastric tumorigenesis that could serve as prognostic indicators and therapeutic targets.” | 0.98 | hgnc_dict_v1 |
| phenotype | gastric cancer | “Comprehensive analysis of aberrantly expressed lncRNAs and construction of ceRNA network in gastric cancer.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | EGFR | “The prediction identified three microRNAs (miR-21, miR-145 and miR-148a) and five gastric cancer-specific target genes (EGFR, KLF4, DNMT1 and AGO4) which also showed strong correlation with lncRNAs in regression analysis.” | 0.98 | hgnc_dict_v1 |
| gene | KLF4 | “The prediction identified three microRNAs (miR-21, miR-145 and miR-148a) and five gastric cancer-specific target genes (EGFR, KLF4, DNMT1 and AGO4) which also showed strong correlation with lncRNAs in regression analysis.” | 0.98 | hgnc_dict_v1 |