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MYD88 and inflammatory bowel disease are reported together in 1 article.
Gene
MYD88
- HGNC
- HGNC:7562
17articles
17mentions
0variants with confirmed gene link
Most co-reported phenotypes (articles)
Phenotype
Inflammatory bowel disease
693articles
693mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Rutin mitigates acetic acid-induced ulcerative colitis: novel coloprotective mechanism.
PMID 39119265 | PMCID PMC11303854 | DOI 10.1093/toxres/tfae108 · Toxicology research · 2024 · 5 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | MYD88 | “Rutin is a natural flavonoid with many pharmacological activities and its role in acetic acid-induced ulcerative colitis through the high mobility group B1 (HMGB1)/ toll-like receptor-4 (TLR4)/ myeloid differentiation primary response protein 88 (MYD88)/ nuclear factor-kB (NF-kB) signaling pathway needs to be explored.” | 0.98 | hgnc_dict_v1 |
| phenotype | inflammatory bowel disease | “BACKGROUND: Ulcerative colitis, an inflammatory bowel disease, is characterized by a status of oxidative stress and inflammation.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | HMGB1 | “Rutin is a natural flavonoid with many pharmacological activities and its role in acetic acid-induced ulcerative colitis through the high mobility group B1 (HMGB1)/ toll-like receptor-4 (TLR4)/ myeloid differentiation primary response protein 88 (MYD88)/ nuclear factor-kB (NF-kB) signaling pathway needs to be explored.” | 0.98 | hgnc_dict_v1 |
| gene | TLR4 | “Rutin is a natural flavonoid with many pharmacological activities and its role in acetic acid-induced ulcerative colitis through the high mobility group B1 (HMGB1)/ toll-like receptor-4 (TLR4)/ myeloid differentiation primary response protein 88 (MYD88)/ nuclear factor-kB (NF-kB) signaling pathway needs to be explored.” | 0.98 | hgnc_dict_v1 |