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NAT2 and thyroid cancer are reported together in 1 article.
Gene
NAT2
- HGNC
- HGNC:7646
14articles
14mentions
4variants with confirmed gene link
Most co-reported phenotypes (articles)
tuberculosis 3colorectal cancer 2diabetes mellitus 2leukemia 2rheumatoid arthritis 2cystic fibrosis 1hepatitis C 1thyroid cancer 1
Reported variants (articles · ClinVar status)
Phenotype
Thyroid cancer
216articles
216mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Polymorphisms of selected xenobiotic genes contribute to the development of papillary thyroid cancer susceptibility in Middle Eastern population.
PMID 18601742 | PMCID PMC2492854 | DOI 10.1186/1471-2350-9-61 · BMC medical genetics · 2008 · 14 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | NAT2 | “METHODS: 223 incident papillary thyroid cancer cases and 513 controls recruited from Saudi Arabian population were analyzed for the association between polymorphisms in genes encoding folic acid metabolizing enzymes MTHFR and six xenobiotics-metabolizing enzymes including CYP1A1 T3801C, C4887A, GSTP1 A1578G, C2293T, GSTM1, GSTT1, NAT2 G590A, NQO*1 C609T, using PCR-RELP.” | 0.98 | hgnc_dict_v1 |
| phenotype | thyroid cancer | “Polymorphisms of selected xenobiotic genes contribute to the development of papillary thyroid cancer susceptibility in Middle Eastern population.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | MTHFR | “METHODS: 223 incident papillary thyroid cancer cases and 513 controls recruited from Saudi Arabian population were analyzed for the association between polymorphisms in genes encoding folic acid metabolizing enzymes MTHFR and six xenobiotics-metabolizing enzymes including CYP1A1 T3801C, C4887A, GSTP1 A1578G, C2293T, GSTM1, GSTT1, NAT2 G590A, NQO*1 C609T, using PCR-RELP.” | 0.98 | hgnc_dict_v1 |
| gene | CYP1A1 | “METHODS: 223 incident papillary thyroid cancer cases and 513 controls recruited from Saudi Arabian population were analyzed for the association between polymorphisms in genes encoding folic acid metabolizing enzymes MTHFR and six xenobiotics-metabolizing enzymes including CYP1A1 T3801C, C4887A, GSTP1 A1578G, C2293T, GSTM1, GSTT1, NAT2 G590A, NQO*1 C609T, using PCR-RELP.” | 0.98 | hgnc_dict_v1 |