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NEK10 and cystic fibrosis are reported together in 1 article.
Gene
NEK10
- HGNC
- HGNC:18592
4articles
4mentions
0variants with confirmed gene link
Most co-reported phenotypes (articles)
Phenotype
Cystic fibrosis
157articles
157mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60A human ciliopathy reveals essential functions for NEK10 in airway mucociliary clearance.
PMID 31959991 | PMCID PMC7018620 | DOI 10.1038/s41591-019-0730-x · Nature medicine · 2020 · 4 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | NEK10 | “A human ciliopathy reveals essential functions for NEK10 in airway mucociliary clearance.” | 0.98 | hgnc_dict_v1 |
| phenotype | cystic fibrosis | “Mucociliary clearance, the physiological process by which mammalian conducting airways expel pathogens and unwanted surface materials from the respiratory tract, depends on the coordinated function of multiple specialized cell types, including basal stem cells, mucus-secreting goblet cells, motile ciliated cells, cystic fibrosis transmembrane conductance regulator (CFTR)-rich ionocytes, and immune cells1,2.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | CFTR | “Mucociliary clearance, the physiological process by which mammalian conducting airways expel pathogens and unwanted surface materials from the respiratory tract, depends on the coordinated function of multiple specialized cell types, including basal stem cells, mucus-secreting goblet cells, motile ciliated cells, cystic fibrosis transmembrane conductance regulator (CFTR)-rich ionocytes, and immune cells1,2.” | 0.98 | hgnc_dict_v1 |
| phenotype | primary ciliary dyskinesia | “Bronchiectasis, a syndrome of pathological airway dilation associated with impaired mucociliary clearance, may occur sporadically or as a consequence of Mendelian inheritance, for example in cystic fibrosis, primary ciliary dyskinesia (PCD), and select immunodeficiencies3.” | 0.98 | phenotype_alias_lexicon_v2 |