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NOD2 and hepatocellular carcinoma are reported together in 1 article.
Gene
NOD2
- HGNC
- HGNC:5331
13articles
13mentions
3variants with confirmed gene link
Most co-reported phenotypes (articles)
Crohn disease 5inflammatory bowel disease 4congenital cataract 1hepatitis B 1hepatocellular carcinoma 1ulcerative colitis 1
Reported variants (articles · ClinVar status)
Phenotype
Hepatocellular carcinoma
417articles
417mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Genetic variations of NOD2 and MD2 genes in hepatitis B virus infection.
PMID 31485165 | PMCID PMC6717085 | DOI 10.1016/j.sjbs.2016.11.010 · Saudi journal of biological sciences · 2019 · 9 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | NOD2 | “Genetic variations of NOD2 and MD2 genes in hepatitis B virus infection.” | 0.98 | hgnc_dict_v1 |
| phenotype | hepatocellular carcinoma | “HBV-infected patients were categorized into three groups based on the clinical stage of the infection: inactive HBV carriers, active HBV carriers, and patients with liver cirrhosis + hepatocellular carcinoma (HCC).” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | TLR4 | “NOD2 is a member of the NOD-like receptor (NLR) family of pattern recognition receptors (PRRs), while MD-2 is a co-receptor for Toll-like receptor 4 (TLR4), which comprises another group of PRRs.” | 0.98 | hgnc_dict_v1 |
| phenotype | hepatitis B | “Genetic variations of NOD2 and MD2 genes in hepatitis B virus infection.” | 0.98 | phenotype_alias_lexicon_v2 |