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NOTCH3 and breast cancer are reported together in 1 article.
Gene
NOTCH3
- HGNC
- HGNC:7883
17articles
17mentions
2variants with confirmed gene link
Most co-reported phenotypes (articles)
stroke 6colorectal cancer 2diabetes mellitus 2hypertension 2Alzheimer disease 1breast cancer 1intellectual disability 1neurodevelopmental disorder 1
Reported variants (articles · ClinVar status)
Phenotype
Breast cancer
1,211articles
1,211mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60NOTCH Single Nucleotide Polymorphisms in the Predisposition of Breast and Colorectal Cancers in Saudi Patients.
PMID 34257585 | PMCID PMC8262141 | DOI 10.3389/pore.2021.616204 · Pathology oncology research : POR · 2021 · 11 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | NOTCH3 | “Interestingly, the rs1043994 located in NOTCH3 showed gender preference and was found to be significantly associated with colorectal cancers in males.” | 0.98 | hgnc_dict_v1 |
| phenotype | breast cancer | “Breast cancer (BC) is a heterogeneous disease and is one of the most common malignancy affecting women worldwide while colorectal cancer (CRC) is estimated to be the third common cancer and second leading cause of cancer related death globally.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | NOTCH1 | “In this case-control study, TaqMan genotypic analysis of rs3124591 in NOTCH1 and rs3820041 in NOTCH4 did not exhibit association with breast as well as colorectal cancers.” | 0.98 | hgnc_dict_v1 |
| gene | NOTCH4 | “In this case-control study, TaqMan genotypic analysis of rs3124591 in NOTCH1 and rs3820041 in NOTCH4 did not exhibit association with breast as well as colorectal cancers.” | 0.98 | hgnc_dict_v1 |