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PDE4D and Fabry disease are reported together in 1 article.
Gene
PDE4D
- HGNC
- HGNC:8783
4articles
4mentions
1variants with confirmed gene link
Most co-reported phenotypes (articles)
Reported variants (articles · ClinVar status)
Phenotype
Fabry disease
19articles
19mentions
6co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Genetics of ischemic stroke.
PMID 21063358 · Neurosciences (Riyadh, Saudi Arabia) · 2008 · 6 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | PDE4D | “Recent research has implicated some novel genes in the etiology of ischemic stroke, including genes for soluble epoxide hydrolase (sHE), 5-lipoxygenase activating protein (FLAP) and phosphodiesterase 4D (PDE4D).” | 0.98 | hgnc_dict_v1 |
| phenotype | Fabry disease | “Meanwhile, the recent availability of enzyme replacement therapy for Fabry disease and the proven benefits of regular blood transfusion in certain patients with sickle cell disease have greatly altered the outlook of these devastating inherited disorders.” | 0.98 | phenotype_alias_lexicon_v2 |
| phenotype | stroke | “Genetics of ischemic stroke.” | 0.98 | phenotype_alias_lexicon_v2 |
| phenotype | hypertension | “Most cases of ischemic stroke are attributable to hypertension and other risk factors, but in over 20% of cases, the cause is unknown.” | 0.98 | phenotype_alias_lexicon_v2 |